Junjie Yao
Biomedical Engineering
Associate Professor of Biomedical Engineering
Research Interests
Photoacoustic tomography (PAT) technologies, and translating PAT advances into diagnostic and therapeutic applications, especially in functional brain imaging and early cancer theranostics.
Bio
Our mission at PI-Lab is to develop state-of-the-art photoacoustic tomography (PAT) technologies and translate PAT advances into diagnostic and therapeutic applications, especially in functional brain imaging and early cancer theranostics. PAT is the most sensitive modality for imaging rich optical absorption contrast over a wide range of spatial scales at high speed, and is one of the fastest growing biomedical imaging technologies. Using numerous endogenous and exogenous contrasts, PAT can provide high-resolution images at scales covering organelles, cells, tissues, organs, small-animal organisms, up to humans, and can reveal tissue’s anatomical, functional, metabolic, and even histologic properties, with molecular and neuronal specificity.
At PI-Lab, we develop PAT technologies with novel and advanced imaging performance, in terms of spatial resolutions, imaging speed, penetration depth, detection sensitivity, and functionality. We are interested with all aspects of PAT technology innovations, including efficient light illumination, high-sensitivity ultrasonic detection, super-resolution PAT, high-speed imaging acquisition, novel PA genetic contrast, and precise image reconstruction. On top of the technological advancements, we are devoted to serve the broad life science and medical communities with matching PAT systems for various research and clinical needs. With its unique contrast mechanism, high scalability, and inherent functional and molecular imaging capabilities, PAT is well suited for a variety of pre-clinical applications, especially for studying tumor angiogenesis, cancer hypoxia, and brain disorders; it is also a promising tool for clinical applications in procedures such as cancer screening, melanoma staging, and endoscopic examination.
Education
- Ph.D. Washington University in St. Louis, 2012
Positions
- Associate Professor of Biomedical Engineering
- Associate Professor in Neurology
- Affiliate, Duke Global Health Institute
- Faculty Network Member of the Duke Institute for Brain Sciences
- Member of the Duke Cancer Institute
Awards, Honors, and Distinctions
- Early Career Development (CAREER) Award. National Science Foundation (NSF). 2022
- Fellow. Optica (formally OSA). 2022
- 2019 Young Investigator Award. IEEE Photonics Society . 2019
- Collaborative Sciences Award. American Heart Association . 2018
- OSA/Quantel Bright Idea Competition (Finalist). Optical Society of America. 2017
- Seno Medical Best Paper Award. SPIE conference Photons Plus Ultrasound 2016: Imaging and Sensing. 2016
- Seno Medical Best Paper Award. SPIE conference Photons Plus Ultrasound 2015: Imaging and Sensing . 2015
- Seno Medical Best Paper Award. SPIE conference Photons Plus Ultrasound 2013: Imaging and Sensing . 2013
- Chinese Government Award for Outstanding Self-financed Students Aboard. The Education Ministry of China. 2012
- Best Master Dissertation Award. Tsinghua University. 2008
- Comprehensive Student Fellowship. Tsinghua University. 2008
- KangShien Outstanding Graduate Fellowship. Tsinghua University. 2006
- CyrusTang Fellowship (2002-2006). Tsinghua University. 2002
Courses Taught
- BME 792: Continuation of Graduate Independent Study
- BME 791: Graduate Independent Study
- BME 790L: Advanced Topics with the Lab for Graduate Students in Biomedical Engineering
- BME 590: Special Topics in Biomedical Engineering
- BME 553: Deep Tissue Optics (GE, IM)
- BME 494: Projects in Biomedical Engineering (GE)
- BME 493: Projects in Biomedical Engineering (GE)
- BME 394: Projects in Biomedical Engineering (GE)
- BME 303L: Modern Diagnostic Imaging Systems (AC or GE)
Publications
- Lv J, Lan H, Qin A, Sun T, Shao D, Gao F, et al. Dynamic synthetic-scanning photoacoustic tracking monitors hepatic and renal clearance pathway of exogeneous probes in vivo. Light, science & applications. 2024 Oct;13(1):304.
- Wang N, Yao J. Sound Out the Deep Clarity: Super-resolution Photoacoustic Imaging at Depths. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2024 Sep;PP.
- Li D, Wang N, Li M, Mishra A, Tang Y, Vu T, et al. Three-dimensional super-resolution passive cavitation mapping in laser lithotripsy. IEEE Trans Ultrason Ferroelectr Freq Control. 2024 Aug 16;PP.
- Mu X, Ma C, Mei X, Liao J, Bojar R, Kuang S, et al. On-demand expansion fluorescence and photoacoustic microscopy (ExFLPAM). Photoacoustics. 2024 Aug;38:100610.
- Yao R, DiSpirito A, Jang H, McGarraugh CT, Nguyen VT, Shi L, et al. Virtual-point-based deconvolution for optical-resolution photoacoustic microscopy. Journal of biophotonics. 2024 Jun;e202400078.
- Maharjan S, Ma C, Singh B, Kang H, Orive G, Yao J, et al. Advanced 3D imaging and organoid bioprinting for biomedical research and therapeutic applications. Advanced drug delivery reviews. 2024 May;208:115237.
- Epstein AA, Janos SN, Menozzi L, Pegram K, Jain V, Bisset LC, et al. Subventricular zone stem cell niche injury is associated with intestinal perforation in preterm infants and predicts future motor impairment. Cell Stem Cell. 2024 Apr 4;31(4):467-483.e6.
- Zhu X, Huang Q, Jiang L, Nguyen V-T, Vu T, Devlin G, et al. Longitudinal intravital imaging of mouse placenta. Sci Adv. 2024 Mar 22;10(12):eadk1278.
- Zhang W, Li Y, Fung AA, Li Z, Jang H, Zha H, et al. Multi-molecular hyperspectral PRM-SRS microscopy. Nat Commun. 2024 Feb 21;15(1):1599.
- Vu T, Klippel P, Canning AJ, Ma C, Zhang H, Kasatkina LA, et al. On the Importance of Low-Frequency Signals in Functional and Molecular Photoacoustic Computed Tomography. IEEE Trans Med Imaging. 2024 Feb;43(2):771–83.
- Vu T, Klippel P, Canning AJ, Ma C, Zhang H, Kasatkina LA, et al. On the Importance of Low-Frequency Signals in Functional and Molecular Photoacoustic Computed Tomography. IEEE transactions on medical imaging. 2024 Feb;43(2):771–83.
- Cho S-W, Nguyen VT, DiSpirito A, Yang J, Kim C-S, Yao J. Sounding out the dynamics: a concise review of high-speed photoacoustic microscopy. Journal of biomedical optics. 2024 Jan;29(Suppl 1):S11521.
- Lin L, Yao J. Photoacoustic imaging. In: Transpathology: Molecular Imaging-Based Pathology. 2024. p. 81–94.
- Xiang G, Chen J, Ho D, Sankin G, Zhao X, Liu Y, et al. Shock waves generated by toroidal bubble collapse are imperative for kidney stone dusting during Holmium:YAG laser lithotripsy. Ultrasonics sonochemistry. 2023 Dec;101:106649.
- Lee Y, Rong Q, Song K-H, Czaplewski DA, Zhang HF, Yao J, et al. Theoretical and experimental study on the detection limit of the micro-ring resonator based ultrasound point detectors. Photoacoustics. 2023 Dec;34:100574.
- Kuang X, Rong Q, Belal S, Vu T, López López AM, Wang N, et al. Self-enhancing sono-inks enable deep-penetration acoustic volumetric printing. Science (New York, NY). 2023 Dec;382(6675):1148–55.
- Rong Q, Taboada C, Águila ÁD, Merutka I, Jayasundara N, Zeng Y, et al. From Ultraviolet to Near-Infrared: Label-Free Reflection-Mode Hyperspectral Photoacoustic Microscopy for Single-Cell Biochemical Mapping. GEN Biotechnology. 2023 Oct 1;2(5):435–44.
- Park H, Yao J, Jing Y. A frequency-domain model-based reconstruction method for transcranial photoacoustic imaging: A 2D numerical investigation. Photoacoustics. 2023 Oct;33:100561.
- Yao J, Kim C, Kolios M, Hu S. Editorial: Breaking the speed limits in photoacoustic microscopy. Photoacoustics. 2023 Aug;32:100541.
- Wu H, Tang Y, Zhang B, Klippel P, Jing Y, Yao J, et al. Miniaturized Stacked Transducer for Intravascular Sonothrombolysis With Internal-Illumination Photoacoustic Imaging Guidance and Clot Characterization. IEEE transactions on bio-medical engineering. 2023 Aug;70(8):2279–88.
- Ma C, Kuang X, Chen M, Menozzi L, Jiang L, Zhou Q, et al. Multiscale photoacoustic tomography using reversibly switchable thermochromics. Journal of biomedical optics. 2023 Aug;28(8):082804.
- Zhang D, Wang W, Zhu X, Li R, Liu W, Chen M, et al. Epinephrine-induced Effects on Cerebral Microcirculation and Oxygenation Dynamics Using Multimodal Monitoring and Functional Photoacoustic Microscopy. Anesthesiology. 2023 Aug 1;139(2):173–85.
- Kim H, Zhang B, Wu H, Yao J, Shi C, Jiang X. Vortex-ultrasound for microbubble-mediated thrombolysis of retracted clots. Applied physics letters. 2023 Aug;123(7):073701.
- Tang Y, Dong Z, Wang N, Del Aguila A, Johnston N, Vu T, et al. Non-invasive Deep-Brain Imaging with 3D Integrated Photoacoustic Tomography and Ultrasound Localization Microscopy (3D-PAULM). ArXiv. 2023 Jul 27;
- Menozzi L, Del Águila Á, Vu T, Ma C, Yang W, Yao J. Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT) for NonInvasive Whole-Brain Imaging of Ischemic Stroke. J Vis Exp. 2023 Jun 2;(196).
- Veverka M, Menozzi L, Yao J. The sound of blood: photoacoustic imaging in blood analysis. Med Nov Technol Devices. 2023 Jun;18.
- Li R, Duan W, Zhang D, Hoffmann U, Yao J, Yang W, et al. Mouse Cardiac Arrest Model for Brain Imaging and Brain Physiology Monitoring During Ischemia and Resuscitation. J Vis Exp. 2023 Apr 14;(194).
- Wang R, Zhu J, Xia J, Yao J, Shi J, Li C. Photoacoustic imaging with limited sampling: a review of machine learning approaches. Biomedical optics express. 2023 Apr;14(4):1777–99.
- Wang Z, Li Q, Kolls BJ, Mace B, Yu S, Li X, et al. Sustained overexpression of spliced X-box-binding protein-1 in neurons leads to spontaneous seizures and sudden death in mice. Commun Biol. 2023 Mar 9;6(1):252.
- Jing Y, Li M, Gu J, Zhong P, Yao J. Time-resolved passive cavitation mapping using the transient angular spectrum approach. In: The Journal of the Acoustical Society of America. Acoustical Society of America (ASA); 2023. p. A268–A268.
- Oliinyk OS, Ma C, Pletnev S, Baloban M, Taboada C, Sheng H, et al. Author Correction: Deep-tissue SWIR imaging using rationally designed small red-shifted near-infrared fluorescent protein. Nat Methods. 2023 Mar;20(3):469.
- Yao J. Deep-tissue photoacoustic imaging of photoswitchable transgenic mouse models. In: The Journal of the Acoustical Society of America. Acoustical Society of America (ASA); 2023. p. A152–A152.
- Yao J. Real-time passive cavitation mapping with high spatial-temporal resolution. In: The Journal of the Acoustical Society of America. Acoustical Society of America (ASA); 2023. p. A315–A315.
- Xiang G, Li D, Chen J, Mishra A, Sankin G, Zhao X, et al. Dissimilar cavitation dynamics and damage patterns produced by parallel fiber alignment to the stone surface in holmium:yttrium aluminum garnet laser lithotripsy. Physics of fluids (Woodbury, NY : 1994). 2023 Mar;35(3):033303.
- Yao J, Nguyen VT. High-Speed Photoacoustic Microscopy Captures Processes Within Tissue. Biophotonics International. 2023 Mar 1;30(2):29–34.
- Cupil-Garcia V, Li JQ, Norton SJ, Odion RA, Strobbia P, Menozzi L, et al. Plasmonic nanorod probes' journey inside plant cells for in vivo SERS sensing and multimodal imaging. Nanoscale. 2023 Mar;15(13):6396–407.
- Menozzi L, Del Águila Á, Vu T, Ma C, Yang W, Yao J. Three-dimensional non-invasive brain imaging of ischemic stroke by integrated photoacoustic, ultrasound and angiographic tomography (PAUSAT). Photoacoustics. 2023 Feb;29:100444.
- Tang Y, Tang S, Huang C, Klippel P, Ma C, Caso N, et al. High-fidelity deep functional photoacoustic tomography enhanced by virtual point sources. Photoacoustics. 2023 Feb;29:100450.
- Oliinyk OS, Ma C, Pletnev S, Baloban M, Taboada C, Sheng H, et al. Deep-tissue SWIR imaging using rationally designed small red-shifted near-infrared fluorescent protein. Nat Methods. 2023 Jan;20(1):70–4.
- Shijo V, Vu T, Yao J, Xu W, Xia J. SwinIR for Photoacoustic Computed Tomography Artifact Reduction. In: IEEE International Ultrasonics Symposium, IUS. 2023.
- Taboada C, Delia J, Chen M, Ma C, Peng X, Zhu X, et al. Glassfrogs conceal blood in their liver to maintain transparency. Science (New York, NY). 2022 Dec;378(6626):1315–20.
- Yao J, Zhou Z, Li L, Chen Y, Wang C, Wang X, et al. Zero-Dimensional Cs3BiX6 (X = Br, Cl) Single Crystal Films with Second Harmonic Generation. Nanoscale research letters. 2022 Dec;17(1):115.
- Chen M, Jiang L, Cook C, Zeng Y, Vu T, Chen R, et al. High-speed wide-field photoacoustic microscopy using a cylindrically focused transparent high-frequency ultrasound transducer. Photoacoustics. 2022 Dec;28:100417.
- Kilian HI, Ma C, Zhang H, Chen M, Nilam A, Quinn B, et al. Intraperitoneal administration for sustained photoacoustic contrast agent imaging. Photoacoustics. 2022 Dec;28:100406.
- Li M, Beaumont N, Ma C, Rojas J, Vu T, Harlacher M, et al. Three-Dimensional Deep-Tissue Functional and Molecular Imaging by Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT). IEEE Trans Med Imaging. 2022 Oct;41(10):2704–14.
- Zhang R, Li LS, Rao B, Rong H, Sun M-Y, Yao J, et al. Multiscale photoacoustic tomography of neural activities with GCaMP calcium indicators. Journal of biomedical optics. 2022 Sep;27(9).
- Chen J, Li D, Yu W, Ma Z, Li C, Xiang G, et al. The Effects of Scanning Speed and Standoff Distance of the Fiber on Dusting Efficiency during Short Pulse Holmium: YAG Laser Lithotripsy. J Clin Med. 2022 Aug 28;11(17).
- Zhang W, Li Y, Fung AA, Li Z, Jang H, Zha H, et al. Multi-Molecular Hyperspectral PRM-SRS Imaging. Cold Spring Harbor Laboratory. 2022.
- Zhu X, Huang Q, DiSpirito A, Vu T, Rong Q, Peng X, et al. Real-time whole-brain imaging of hemodynamics and oxygenation at micro-vessel resolution with ultrafast wide-field photoacoustic microscopy. Light Sci Appl. 2022 May 17;11(1):138.
- Kasatkina LA, Ma C, Matlashov ME, Vu T, Li M, Kaberniuk AA, et al. Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model. Nature communications. 2022 May;13(1):2813.
- Tang Y, Wu H, Klippel P, Zhang B, Huang H-YS, Jing Y, et al. Deep thrombosis characterization using photoacoustic imaging with intravascular light delivery. Biomedical engineering letters. 2022 May;12(2):135–45.
- Zhang H, Bo W, Wang D, DiSpirito A, Huang C, Nyayapathi N, et al. Deep-E: A Fully-Dense Neural Network for Improving the Elevation Resolution in Linear-Array-Based Photoacoustic Tomography. IEEE transactions on medical imaging. 2022 May;41(5):1279–88.
- Yao J, Liu C, Pang T, Li J, Lei S, Zhang J, et al. Joint mobilization for frozen shoulder: A protocol for systematic review and meta-analysis. Medicine. 2022 Apr;101(14):e29123.
- Liu C, Pang T, Yin S, Li J, Yao J, Li H, et al. Curative efficiency and adverse events of alternative therapy and medicine for functional constipation in adults: A protocol for systematic review and meta-analysis. Medicine. 2022 Apr;101(14):e29082.
- Duan T, Peng X, Chen M, Zhang D, Gao F, Yao J. Detection of weak optical absorption by optical-resolution photoacoustic microscopy. Photoacoustics. 2022 Mar;25:100335.
- Pang T, Liu C, Li J, Yao J, Li Z, Lei S, et al. Effectiveness and safety of aromatherapy massage for knee osteoarthritis: A protocol for systematic review and meta-analysis. Medicine. 2022 Mar;101(11):e29039.
- Qiao L, Men L, Yu S, Yao J, Li Y, Wang M, et al. Hepatic deficiency of selenoprotein S exacerbates hepatic steatosis and insulin resistance. Cell death & disease. 2022 Mar;13(3):275.
- Liu C, Pang T, Yao J, Li J, Lei S, Zhang J, et al. Acupuncture and massage combined with rehabilitation therapy for hemiplegia after stroke: A protocol for systematic review and meta-analysis. Medicine. 2022 Feb;101(6):e28732.
- Ma C, Li W, Li D, Chen M, Wang M, Jiang L, et al. Photoacoustic imaging of 3D-printed vascular networks. Biofabrication. 2022 Jan;14(2).
- Menozzi L, Yang W, Feng W, Yao J. Sound out the impaired perfusion: Photoacoustic imaging in preclinical ischemic stroke. Frontiers in neuroscience. 2022 Jan;16:1055552.
- Čiževskis O, Cugmas B, Viškere D, Melderis M, Liepniece-Karele I, Yao J, et al. Tumour classification with optimized sliding window size for OCT imaging. In: Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2022.
- Dong B, Yao J, Deán-Ben XL. Editorial: Advances in Photoacoustic Neuroimaging. Frontiers in neuroscience. 2022 Jan;16:859515.
- Rong Q, Lee Y, Tang Y, Vu T, Taboada C, Zheng W, et al. High-Frequency 3D Photoacoustic Computed Tomography Using an Optical Microring Resonator. BME frontiers. 2022 Jan;2022:9891510.
- Wang Z, Li Y, Yao J, Yu S, Yu H, Men L, et al. Selenoprotein S attenuates high glucose and/or ox-LDL-induced endothelium injury by regulating Akt/mTOR signaling and autophagy. The international journal of biochemistry & cell biology. 2021 Dec;141:106111.
- Chen M, Duan X, Lan B, Vu T, Zhu X, Rong Q, et al. High-speed functional photoacoustic microscopy using a water-immersible two-axis torsion-bending scanner. Photoacoustics. 2021 Dec;24:100309.
- Wang J, Ma L, Wang X, Yao J, Yi Q, Tang R, et al. Sub-Nanometer Thick Wafer-Size NiO Films with Room-Temperature Ferromagnetic Behavior. Angewandte Chemie (International ed in English). 2021 Nov;60(47):25020–7.
- Vu T, Tang Y, Li M, Sankin G, Tang S, Chen S, et al. Photoacoustic computed tomography of mechanical HIFU-induced vascular injury. Biomedical optics express. 2021 Sep;12(9):5489–98.
- Li X, Yao J, Zhang W, Chen S, Peng W. Effects of transcranial direct current stimulation on experimental pain perception: A systematic review and meta-analysis. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2021 Sep;132(9):2163–75.
- Li D, Humayun L, Vienneau E, Vu T, Yao J. Seeing through the Skin: Photoacoustic Tomography of Skin Vasculature and Beyond. JID innovations : skin science from molecules to population health. 2021 Sep;1(3):100039.
- Li H, Cheng F, Orgill DP, Yao J, Zhang YS. Handheld bioprinting strategies for in situ wound dressing. Essays in biochemistry. 2021 Aug;65(3):533–43.
- Mac Grory B, Schrag M, Poli S, Boisvert CJ, Spitzer MS, Schultheiss M, et al. Structural and Functional Imaging of the Retina in Central Retinal Artery Occlusion - Current Approaches and Future Directions. J Stroke Cerebrovasc Dis. 2021 Jul;30(7):105828.
- Zhang D, Li R, Chen M, Vu T, Sheng H, Yang W, et al. Photoacoustic imaging of in vivo hemodynamic responses to sodium nitroprusside. J Biophotonics. 2021 Jul;14(7):e202000478.
- Xia J, Lediju Bell MA, Laufer J, Yao J. Translational Photoacoustic Imaging for Disease Diagnosis, Monitoring, and Surgical Guidance: introduction to the feature issue. Biomedical optics express. 2021 Jul;12(7):4115–8.
- Li M, Gu J, Vu T, Sankin G, Zhong P, Yao J, et al. Time-Resolved Passive Cavitation Mapping Using the Transient Angular Spectrum Approach. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2021 Jul;68(7):2361–9.
- Vu T, DiSpirito A, Li D, Wang Z, Zhu X, Chen M, et al. Deep image prior for undersampling high-speed photoacoustic microscopy. Photoacoustics. 2021 Jun 1;22.
- Yao J, Wang LV. Perspective on fast-evolving photoacoustic tomography. Journal of biomedical optics. 2021 Jun;26(6).
- ZHANG W, LI X, YAO J, YE Q, PENG W. Abnormalities in pain sensitivity among individuals with autism spectrum disorder: Evidence from meta-analysis. Acta Psychologica Sinica. 2021 Jun 1;53(6):613–28.
- Vu T, DiSpirito A, Li D, Wang Z, Zhu X, Chen M, et al. Deep image prior for undersampling high-speed photoacoustic microscopy. Photoacoustics. 2021 Jun;22:100266.
- DiSpirito A, Vu T, Pramanik M, Yao J. Sounding out the hidden data: A concise review of deep learning in photoacoustic imaging. Experimental biology and medicine (Maywood, NJ). 2021 Jun;246(12):1355–67.
- Li H, Wu Z, Zhang J, Sun X, Duan F, Yao J, et al. Instant Ultrasound-Evoked Precise Nanobubble Explosion and Deep Photodynamic Therapy for Tumors Guided by Molecular Imaging. ACS applied materials & interfaces. 2021 May;13(18):21097–107.
- Xie Y, Zhao B, Tang K, Qin W, Tan C, Yao J, et al. In-situ phase transition induced nanoheterostructure for overall water splitting. Chemical Engineering Journal. 2021 Apr;409:128156–128156.
- Li X, Guan J, Jiang Z, Cheng S, Hou W, Yao J, et al. Microglial Exosome miR-7239-3p Promotes Glioma Progression by Regulating Circadian Genes. Neuroscience bulletin. 2021 Apr;37(4):497–510.
- Shemetov AA, Monakhov MV, Zhang Q, Canton-Josh JE, Kumar M, Chen M, et al. A near-infrared genetically encoded calcium indicator for in vivo imaging. Nat Biotechnol. 2021 Mar;39(3):368–77.
- Tang Y, Yao J. 3D Monte Carlo simulation of light distribution in mouse brain in quantitative photoacoustic computed tomography. Quantitative imaging in medicine and surgery. 2021 Mar;11(3):1046–59.
- Liang B, Wang S, Shen F, Liu QH, Gong Y, Yao J. Acoustic impact of the human skull on transcranial photoacoustic imaging. Biomedical optics express. 2021 Mar;12(3):1512–28.
- Luo F, Hao X, Jia Y, Yao J, Meng Q, Zhai S, et al. Functionalization induced quantum spin Hall to quantum anomalous Hall phase transition in monolayer jacutingaite. Nanoscale. 2021 Feb;13(4):2527–33.
- Li M, Sankin G, Vu T, Yao J, Zhong P. Tri-modality cavitation mapping in shock wave lithotripsy. The Journal of the Acoustical Society of America. 2021 Feb;149(2):1258.
- DiSpirito A, Li D, Vu T, Chen M, Zhang D, Luo J, et al. Reconstructing Undersampled Photoacoustic Microscopy Images Using Deep Learning. IEEE transactions on medical imaging. 2021 Feb;40(2):562–70.
- Fang B, Yao J, Zhang X, Ma L, Ye Y, Tang J, et al. A large scaled-up monocrystalline 3R MoS2 electrocatalyst for efficient nitrogen reduction reactions. New Journal of Chemistry. 2021;45(5):2488–95.
- Yang L, Wang Y, Feng H, Zeng H, Tan C, Yao J, et al. PdAg Nanoparticles with Different Sizes: Facile One-Step Synthesis and High Electrocatalytic Activity for Formic Acid Oxidation. Chemistry, an Asian journal. 2021 Jan;16(1):34–8.
- Humayun L, Smith C, Li W, Zhang YS, Park C, Feng W, et al. SARS-CoV-2-related vascular injury: mechanisms, imaging and models. Microphysiol Syst. 2021 Jan;5.
- III AD, Li D, Vu T, Chen M, Zhang D, Luo J, et al. Reconstructing Undersampled Photoacoustic Microscopy Images Using Deep Learning. IEEE Trans Medical Imaging. 2021;40:562–70.
- Li M, Vu T, Sankin G, Winship B, Boydston K, Terry R, et al. Internal-Illumination Photoacoustic Tomography Enhanced by a Graded-Scattering Fiber Diffuser. IEEE transactions on medical imaging. 2021 Jan;40(1):346–56.
- Yao J, Wang LV. Photoacoustic Molecular Imaging: Principles and Practice. In: Molecular Imaging: Principles and Practice. 2021. p. 233–44.
- Wang S, Chen Y, Yao J, Zhao G, Li L, Zou G. Wafer-sized 2D perovskite single crystal thin films for UV photodetectors. Journal of Materials Chemistry C. 2021;9(20):6498–506.
- Liu Y, Cheng X, Qin L, Wang X, Yao J, Wu H. Experimental investigation on soot formation characteristics of n-heptane/butanol isomers blends in laminar diffusion flames. Energy. 2020 Nov;211:118714–118714.
- Wu H, Tang Y, Kim H, Yao J, Jiang X. Fiber based laser ultrasound transducer for intravascular thrombolysis with detective photoacoustic imaging. In: IEEE International Ultrasonics Symposium, IUS. 2020.
- Yao J, Hao X, Luo F, Jia Y, Zhou M. Quadrupole topological phase and robust corner resonance in Kekulé hexagonal electric circuit. New Journal of Physics. 2020 Sep 1;22(9):093029–093029.
- Li M, Yao J. Internal-Illumination Photoacoustic Tomography Enhanced by a Graded-scattering Fiber Diffuser. In: 2020 IEEE Photonics Conference, IPC 2020 - Proceedings. 2020.
- Yao J. Ultrasfast Wide-field Photoacoustic Microscopy of Small-animal Models. In: 2020 IEEE Photonics Conference, IPC 2020 - Proceedings. 2020.
- Nief CA, Chelales E, Morhard R, Chem M, Everitt J, Mueller J, et al. Abstract 5243: Averting tumor growth in rodent breast cancer models with a liquid ablation approach. In: Cancer Research. American Association for Cancer Research (AACR); 2020. p. 5243–5243.
- Zhong Y, Yu S, Yu H, Yao J, Men L, Li Y, et al. Selenoprotein S attenuates endothelial dysfunction in a diabetic vascular chip. Experimental gerontology. 2020 Aug;137:110963.
- Vu T, Li M, Humayun H, Zhou Y, Yao J. A generative adversarial network for artifact removal in photoacoustic computed tomography with a linear-array transducer. Experimental biology and medicine (Maywood, NJ). 2020 Apr;245(7):597–605.
- Zhang R, Wang X, Yu C, Liu J, Yao J, Kang X, et al. Preparation of Multiferroic YFeO3 Nanofibers and the Photocatalytic Activity under Visible Irradiation. Integrated Ferroelectrics. 2020 Mar 23;206(1):105–11.
- Men L, Yao J, Yu S, Li Y, Cui S, Jin S, et al. Selenoprotein S regulates adipogenesis through IRE1α-XBP1 pathway. The Journal of endocrinology. 2020 Mar;244(3):431–43.
- Li Y, Li L, Zhu L, Maslov K, Shi J, Hu P, et al. Snapshot Photoacoustic Topography Through an Ergodic Relay for High-throughput Imaging of Optical Absorption. Nature photonics. 2020 Mar;14(3):164–70.
- Li X, Guan J, Sun T, Yang J, Yu H, Yao J, et al. Circadian learning and memory changes in Aβ1-42 induced Alzheimer's mice. Metabolic brain disease. 2020 Mar;35(3):463–71.
- Li M, Lan B, Sankin G, Zhou Y, Liu W, Xia J, et al. Simultaneous Photoacoustic Imaging and Cavitation Mapping in Shockwave Lithotripsy. IEEE transactions on medical imaging. 2020 Feb;39(2):468–77.
- Eckersley CP, Op’T Eynde J, Abrams MZ, Yu AW, Li M, Yao J, et al. Acoustic Detection of Blunt-Induced Cavitation in the Head. In: Conference proceedings International Research Council on the Biomechanics of Injury, IRCOBI. 2020. p. 709–22.
- Li L, Yao J, Wang LV. Photoacoustic Tomography of Neural Systems. In: Neural Engineering: Third Edition. 2020. p. 349–78.
- Tang Y, Qian X, Lee DJ, Zhou Q, Yao J. From Light to Sound: Photoacoustic and Ultrasound Imaging in Fundamental Research of Alzheimer's Disease. OBM neurobiology. 2020 Jan;4(2).
- Li M, Nyayapathi N, Kilian HI, Xia J, Lovell JF, Yao J. Sound Out the Deep Colors: Photoacoustic Molecular Imaging at New Depths. Molecular imaging. 2020 Jan;19:1536012120981518.
- Onufer EJ, Aladegbami B, Imai T, Seiler K, Bajinting A, Courtney C, et al. EGFR in enterocytes & endothelium and HIF1α in enterocytes are dispensable for massive small bowel resection induced angiogenesis. PloS one. 2020 Jan;15(9):e0236964.
- Vienneau E, Vu T, Yao J. Photoacoustic imaging of skin. In: Imaging Technologies and Transdermal Delivery in Skin Disorders. 2019. p. 411–42.
- Vu T, Razansky D, Yao J. Listening to tissues with new light: recent technological advances in photoacoustic imaging. Journal of optics (2010). 2019 Oct;21(10).
- Wu W, Yao J, Liu S, Zhao L, Xu L, Sun Y, et al. Nanostructured hexagonal ReO3 with oxygen vacancies for efficient electrocatalytic hydrogen generation. Nanotechnology. 2019 Aug;30(35):355701.
- Chen M, Knox HJ, Tang Y, Liu W, Nie L, Chan J, et al. Simultaneous photoacoustic imaging of intravascular and tissue oxygenation. Optics letters. 2019 Aug;44(15):3773–6.
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- Yao J, Maslov K, Hu S, Wang LV. Evans blue dye-enhanced capillary-resolution photoacoustic microscopy in vivo. Journal of biomedical optics. 2009 Sep;14(5):054049.
- Song XL, Hu G, Yao JJ, Bai J. Three-dimensional reconstruction for fluorescence tomography using cylinder phantoms. Ruan Jian Xue Bao/Journal of Software. 2009 May 1;20(5):1089–95.
- Yao JJ, Hu G, Bai J. Modeling and validation of light propagation in free-space for non-contact near-infrared fluorescent tomography. Hongwai Yu Haomibo Xuebao/Journal of Infrared and Millimeter Waves. 2008 Oct 1;27(5).
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In The News
- Research & Innovation Seed Grants Total Nearly $2 Million (Dec 3, 2024 | Duke Today)
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- Lasers, Lenses & Light: A Showcase of Fitzpatrick Institute Photonics Research for the Community (Apr 30, 2024 | Duke Today)
- Wearable Imaging Tool Would Make It Easier to Diagnose Neurological Issues (Jul 27, 2023 | Pratt School of Engineering)
- Glassfrogs Hide Red Blood Cells in Their Liver to Become Transparent (Jan 3, 2023 | Pratt School of Engineering)
- Using Light and Sound to Reveal Rapid Brain Activity in Unprecedented Detail (May 31, 2022 | Pratt School of Engineering)
- Yao Receives NSF CAREER Award to Monitor the Brain Using Photoacoustic Imaging (Jan 24, 2022 | Duke Engineering News)
- Check This Out: The Brain During a Heart Attack (Nov 12, 2020 | )
- Novel Light and Sound Imaging Could Greatly Enhance Cancer Therapies (Feb 13, 2019 | Pratt School of Engineering)
- Listening to Blood (Jul 27, 2018 | Duke University School of Medicine Alumni News Magazine)
- Lasers Make Sound Waves That Reveal Live Views of Organs in Action (May 10, 2017 | Pratt School of Engineering)
- Junjie Yao: Listening into the Body through Light (Oct 30, 2016 | )