Olaf T. Von Ramm
Biomedical Engineering
Thomas Lord Distinguished Professor of Engineering
Research Interests
Diagnostic ultrasound imaging systems, IR imaging, medical instrumentation and their new applications.
Bio
Dr. von Ramm's research interests include diagnostic ultrasound imaging systems, IR imaging, medical instrumentation and ntheir new applications.
Ultrasound Imaging. The main direction of research is a development of new ultrasonic techniques for better visualization of the human anatomy, improved ultrasonic detection of tumors and other space occupying lesions as well as improved detection and visualization of blood flow. Several generations of phased array Ultrasound imaging systems have been designed and constructed in our laboratories to assist the clinical value of various novel Ultrasound imaging techniques. Research interests range from basic physics of acoustics and properties of materials required in transducer construction, through the design and construction of advanced imaging systems, to the clinical application and evaluation of new instruments or measurement principles. Of particular interest has been the quantization of cardiac function using Ultrasound.
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High Speed Ultrasound Imaging is a project with a long-term goal to design, construct and clinically evaluate a real-time volumetric (3-D) ultrasonic imaging system which is also capable of visualizing and accurately representing blood flow in three dimensions. This instrument will permit the non-invasive assessment of tumor and organ volumes as well as cardiac chamber volumes. Such measurements have the potential of improving decision on tumor treatment, of assessing congenital and pathological states of various organs and of evaluating cardiac function on a serial basis. Incorporation of angle-independent 3-D flow measurements will permit the rapid noninvasive assessment of flow in major peripheral vessels, deep abdominal vessels and coronary arteries. Flow imaging will also delineate the lumen of the vessel thereby simplifying detection of atherosclerotic clacks. n
Another project Real-Time 3-D Ultrasonic Data Acquisition, is aimed at the design, construction and evaluation of a new generation pulsed array Ultrasound imaging system based on VLSI ASICs and specialized linear integrated circuits. This system will eventually feature256 parallel receive channels with 64 to 1 parallel processing. Up to 64simultaneous B-mode will be acquired in real time so that virtually any view of the anatomy can be visualized on line. n
Scatter Imaging is the focus of yet another research effort which is directed toward imaging with Ultrasound energies scattered at various angles from soft tissue. Studies are directed towards assessing the viability of such imaging and improving contrast between tissue types and generally improving image quality. This method may also permit the quantitative determination of physical tissue parameters such as ultrasonic propagation velocities. n
Medical Center equipment totally dedicated to the Ultrasound work includes the second generation phased array instrument constructed at Duke, a VAX11/780, a Kontron image processor, electronic test equipment, extensive video equipment including an In star 240 frame per second instrument. In addition there are 9 commercial phased array instruments in clinical use with various transducer probes that can be scheduled for research purposes.nn
Cardiovascular Technologies. The National Science Foundation Engineering Research Center for Emerging Cardiovascular Technologies (NSF/ERC) at Duke University incorporates the latest knowledge and methodology in custom integrated electronics, biosensors, system design, and simulation to develop a new generation of Cardiac Interventional and Medical Imaging Systems. This interdisciplinary Center brings together the active research programs of well-established engineering and biomedical researchers and industrial investigators to advance biomedical systems, devices, and instrumentation in the coming decade. Research interests include the study of interventional stimulation and catheterization procedures aimed at the development of a new generation of devices and procedures for the treatment of arrhythmias, atherosclerosis, and other vascular diseases. Research contributors possess highly specialized skills in medical research, biomedical engineering, electrical engineering, mechanical engineering, materials science, and micro electronic technology. All of these skills are required in a systems approach to developing implantable devices and interventional methods.
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n Other research groups focus on the development of high speed 3-D imaging systems including two major projects: 3-D real-time ultrasonic imaging and magnetic resonance microscopy. The extensions of these modalities to dynamic, three-dimensional imaging capabilities should double the present Ultrasound and magnetic resonance imaging sales. These imaging and display systems will also be of major importance in the in vivo evaluation of the systems.
n The vision of current cardiac stimulation research projects is to prevent sudden cardiac death by developing several different types of high technology devices to be implanted within the body. These devices will halt or prevent ventricular fibrillation, the primary cause of sudden cardiac death.
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n The key technical problems blocking advances in the development of devices to prevent sudden cardiac death are a lack of knowledge of (a) the distribution of the electrical field created throughout the heart by a set of stimulating electrodes, (b) the reaction of the heart cells to a given electrical field as a function of the cell's electrophysiologic state at the time of the shock, and (c) the individuals who are at risk for sudden cardiac death and thus are candidates for these devices.
The key research goals and objectives are to obtain and evaluate experimental knowledge by using specially constructed, computer-assisted data acquisition systems and electrode arrays to record the intrinsic electrical activity of the heart before and after a large electrical stimulus, as well as the potentials created throughout the heart by the stimulus itself. The correctness of bioelectric simulation and concepts are assessed by comparing these predictions to the measured data.
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n This work is strongly dependent on the circuits, sensors, and simulation research projects that are significant strengths of the NSF/ERC program. Investigators are developing systems requirements and specifications for array transducers, custom integrated circuits, integrated systems, biosensors, and simulations that focus the core research activities in micro electronics and biosensor design and fabrication.
n A major goal of this Center is to improve engineering educational programs by expanding the opportunities for engineering students to interact with industrial investigators. In particular, the Center is initiating an approach to graduate and undergraduate engineering education in which NSF/ERC Fellows receive substantive advising and individually tailored instruction from leading engineers in industry. n
Education
- B.S. University of Toronto (Canada), 1968
- M.S. University of Toronto (Canada), 1970
- Ph.D. Duke University, 1973
Positions
- Thomas Lord Distinguished Professor of Engineering
- Professor of Biomedical Engineering
- Professor in Medicine
Awards, Honors, and Distinctions
- Fellow. American Institute for Medical and Biological Engineering. 1998
Courses Taught
- BME 543L: Cardiac Ultrasound Imaging and Function (GE, IM)
- BME 542: Principles of Ultrasound Imaging (GE, IM)
- BME 493: Projects in Biomedical Engineering (GE)
- BME 464L: Medical Instrument Design (DR)
Publications
- Moore C, McCrary AW, LeFevre M, Sturgeon GM, Barker PAC, von Ramm OT. Ultrasound Visualization and Recording of Transient Myocardial Vibrations. Ultrasound Med Biol. 2023 Jun;49(6):1431–40.
- Andersen MS, Moore C, LeFevre M, Arges K, Friedman DJ, Atwater BD, et al. Contractile Fronts In The Interventricular Septum: A Case For High Frame Rate Echocardiographic Imaging. Ultrasound Med Biol. 2020 Sep;46(9):2181–92.
- Andersen MV, Moore C, Søgaard P, Friedman D, Atwater BD, Arges K, et al. Quantitative Parameters of High-Frame-Rate Strain in Patients with Echocardiographically Normal Function. Ultrasound Med Biol. 2019 May;45(5):1197–207.
- Andersen M, Moore C, Ages K, Lefevre M, Schmidt S, Kisslo J, et al. Notice of Removal: High speed clinical Strain measurements. In: IEEE International Ultrasonics Symposium, IUS. 2017.
- Andersen MV, Moore C, Arges K, Søgaard P, Østergaard LR, Schmidt SE, et al. High-Frame-Rate Deformation Imaging in Two Dimensions Using Continuous Speckle-Feature Tracking. Ultrasound Med Biol. 2016 Nov;42(11):2606–15.
- Andersen MV, Moore C, Schmidt SE, Sogaard P, Struijk JJ, Kisslo J, et al. Feature tracking algorithm for circumferential strain using high frame rate echocardiography. In: Computing in Cardiology. 2016. p. 885–8.
- Moore C, Castellucci J, Andersen MV, LeFevre M, Arges K, Kisslo J, et al. Live high-frame-rate echocardiography. IEEE Trans Ultrason Ferroelectr Freq Control. 2015 Oct;62(10):1779–87.
- Moore C, Castellucci J, Von Ramm O, Samad Z, Kisslo J. Blood flow visualization with real time high speed ultrasound. In: IEEE International Ultrasonics Symposium, IUS. 2014. p. 1207–8.
- Dausch DE, Gilchrist KH, Carlson JB, Hall SD, Castellucci JB, von Ramm OT. In vivo real-time 3-D intracardiac echo using PMUT arrays. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2014 Oct;61(10):1754–64.
- Dausch DE, Castellucci JB, Gilchrist KH, Carlson JB, Hall SD, von Ramm OT. Live volumetric imaging (LVI) intracardiac ultrasound catheter. Cardiovascular revascularization medicine : including molecular interventions. 2013 May;14(3):157–9.
- Pellikka PA, Douglas PS, Miller JG, Abraham TP, Baumann R, Buxton DB, et al. American Society of Echocardiography Cardiovascular Technology and Research Summit: a roadmap for 2020. J Am Soc Echocardiogr. 2013 Apr;26(4):325–38.
- Dianis SW, von Ramm OT. Harmonic source wavefront aberration correction for ultrasound imaging. The Journal of the Acoustical Society of America. 2011 Jan;129(1):507–17.
- Dausch DE, Gilchrist KH, Carlson JR, Castellucci JB, Chou DR, Von Ramm OT. Improved pulse-echo imaging performance for flexure-mode pMUT arrays. Proceedings - IEEE Ultrasonics Symposium. 2010 Dec 1;451–4.
- Dianis SW, Von Ramm OT. Assessment of harmonic source correction for ultrasound medical imaging. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2010 Sep 24;7629.
- Dianis SW, Von Ramm OT. The first harmonic as a known source for wavefront correction. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2009 Jun 19;7265.
- Dausch DE, Castellucci JB, Chou DR, von Ramm OT. Theory and operation of 2-D array piezoelectric micromachined ultrasound transducers. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2008 Nov;55(11):2484–92.
- Kuo J, von Ramm OT. Three-dimensional motion measurements using feature tracking. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2008 Apr;55(4):800–10.
- Dausch DE, Gilchrist KH, Castellucci JB, Chou DR, Von Ramm OT. Performance of flexure-mode pMUT 2D arrays. Proceedings - IEEE Ultrasonics Symposium. 2007 Dec 1;1053–6.
- Wang L, Chapman J, Palmer RA, van Ramm O, Mizaikoff B. Classification of atherosclerotic rabbit aorta samples by mid-infrared spectroscopy using multivariate data analysis. Journal of biomedical optics. 2007 Mar;12(2):024006.
- Kuo J, Bredthauer GR, Castellucci JB, von Ramm OT. Interactive volume rendering of real-time three-dimensional ultrasound images. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2007 Feb;54(2):313–8.
- Dausch DE, Castellucci JB, Chou DR, Von Ramm OT. Piezoelectric micromachined ultrasound transducer (pMUT) arrays for 3D imaging probes. Proceedings - IEEE Ultrasonics Symposium. 2006 Dec 1;1:930–3.
- Stetten G, Cois A, Chang W, Shelton D, Tamburo R, Castellucci J, et al. C-mode real-time tomographic reflection for a matrix array ultrasound sonic flashlight. Academic radiology. 2005 May;12(5):535–43.
- Kuo J, Atkins BZ, Hutcheson KA, von Ramm OT. Left ventricular wall motion analysis using real-time three-dimensional ultrasound. Ultrasound in medicine & biology. 2005 Feb;31(2):203–11.
- Wang L, Chapman J, Palmer RA, Alter TM, Hooper BA, Ramm OV, et al. Classification of Atherosclerotic Rabbit Aorta Samples with an Infrared Attenuated Total Reflection Catheter and Multivariate Data Analysis (Submitted). Appl Spectrosc. 2005;
- Bredthauer GR, Von Ramm OT. Interactive rendering of real-time volumetric ultrasound images. 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano. 2004 Dec 1;1:524–6.
- Li X, Jones M, Irvine T, Rusk RA, Mori Y, Hashimoto I, et al. Real-time 3-dimensional echocardiography for quantification of the difference in left ventricular versus right ventricular stroke volume in a chronic animal model study: Improved results using C-scans for quantifying aortic regurgitation. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography. 2004 Aug;17(8):870–5.
- Atkins BZ, Kuo J, Shah AS, Hutcheson KA, Glower DD, von Ramm OT. Real-time three-dimensional echocardiography to construct clinically ready, load-independent indices of myocardial contractile performance. J Am Soc Echocardiogr. 2003 Sep;16(9):922–30.
- Stetten G, Cois A, Chang W, Shelton D, Tamburo R, Castellucci J, et al. C-mode real time tomographic reflection for a matrix array ultrasound sonic flashlight. Lecture Notes in Computer Science. 2003 Jan 1;2879(PART 2):336–43.
- Morizio J, Guhados S, Castellucci J, Von Ramm O. 64-Channel ultrasound transducer amplifier. In: 2003 Southwest Symposium on Mixed-Signal Design, SSMSD 2003. 2003. p. 228–32.
- Pasipoularides AD, Shu M, Womack MS, Shah A, Von Ramm O, Glower DD. RV functional imaging: 3-D echo-derived dynamic geometry and flow field simulations. Am J Physiol Heart Circ Physiol. 2003 Jan;284(1):H56–65.
- Kuo J, Atkins BZ, Von Ramm OT. Left ventricle function analysis with real-time three-dimensional ultrasound. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2002 Dec 1;2:1105–6.
- Bredthauer GR, Von Ramm OT. Ultrasonic transducer simulation and field visualization 2nd joint conference of the IEEE engineering in medicine and biology society and the biomedical engineering society. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2002 Dec 1;2:971–2.
- Bredthauer GR, Von Ramm OT. Array design for ultrasound imaging with simultaneous beams. In: Proceedings - International Symposium on Biomedical Imaging. 2002. p. 981–4.
- Hooper BA, LaVerde GC, Von Ramm OT. Design and construction of an evanescent optical wave device for the recanalization of vessels. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 2001 Nov 21;475(1–3):645–9.
- Irvine T, Stetten GD, Sachdev V, Zetts AD, Jones M, Mori Y, et al. Quantification of aortic regurgitation by real-time 3-dimensional echocardiography in a chronic animal model: computation of aortic regurgitant volume as the difference between left and right ventricular stroke volumes. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography. 2001 Nov;14(11):1112–8.
- Schmidt MA, Freidlin RZ, Ohazama CJ, Jones M, Laurienzo JM, Brenneman CL, et al. Anatomic validation of a novel method for left ventricular volume and mass measurements with use of real-time 3-dimensional echocardiography. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography. 2001 Jan;14(1):1–10.
- Ota T, Kisslo J, von Ramm OT, Yoshikawa J. Real-time, volumetric echocardiography: usefulness of volumetric scanning for the assessment of cardiac volume and function. J Cardiol. 2001;37 Suppl 1:93–101.
- Kisslo J, Firek B, Ota T, Kang DH, Fleishman CE, Stetten G, et al. Real-time volumetric echocardiography: the technology and the possibilities. Echocardiography. 2000 Nov;17(8):773–9.
- Lacefield JC, von Ramm OT. Angular scatter ultrasound imaging of wavelength scale targets. The Journal of the Acoustical Society of America. 2000 Oct;108(4):1914–9.
- von Ramm OT. 2-D arrays. Ultrasound in medicine & biology. 2000 May;26 Suppl 1:S10–2.
- Lacefield JC, von Ramm OT. Design and characterization of a real-time angular scatter ultrasound imaging system. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 2000 Jan;47(1):222–32.
- Schmidt MA, Ohazama CJ, Agyeman KO, Freidlin RZ, Jones M, Laurienzo JM, et al. Real-time three-dimensional echocardiography for measurement of left ventricular volumes. The American journal of cardiology. 1999 Dec;84(12):1434–9.
- Ota T, Fleishman CE, Strub M, Stetten G, Ohazama CJ, von Ramm OT, et al. Real-time, three-dimensional echocardiography: feasibility of dynamic right ventricular volume measurement with saline contrast. Am Heart J. 1999 May;137(5):958–66.
- Morsy AA, Von Ramm OT. FLASH correlation: a new method for 3-D ultrasound tissue motion tracking and blood velocity estimation. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 1999 Jan;46(3):728–36.
- Morsy AA, Von Ramm OT. 3D ultrasound tissue motion tracking using correlation search. Ultrasonic imaging. 1998 Jul;20(3):151–9.
- Shiota T, Jones M, Chikada M, Fleishman CE, Castellucci JB, Cotter B, et al. Real-time three-dimensional echocardiography for determining right ventricular stroke volume in an animal model of chronic right ventricular volume overload. Circulation. 1998 May 19;97(19):1897–900.
- Nosé Y, Tsutsui T, Butler KC, Jarvik R, Takami Y, Nojiri C, et al. Rotary pumps: new developments and future perspectives. ASAIO journal (American Society for Artificial Internal Organs : 1992). 1998 May;44(3):234–7.
- Stetten GD, Ota T, Ohazama CJ, Fleishman C, Castellucci J, Oxaal J, et al. Real-time 3D ultrasound: A new look at the heart. Journal of Cardiovascular Diagnosis and Procedures. 1998 Jan 1;15(2):73–84.
- Drezek RA, Stetten GD, Ota T, Fleishman C, Lily E, Lewis C, et al. Active contour based on the elliptical Fourier series, applied to matrix-array ultrasound of the heart. In: Proceedings of SPIE - The International Society for Optical Engineering. 1997. p. 26–34.
- Morsy AA, Stetten GD, Von Ramm OT. Detection and quantification of true 3D motion components of the myocardium using 3D speckle tracking in volumetric ultrasound scans: simulations and initial experimental results. Proceedings of SPIE - The International Society for Optical Engineering. 1997;3033:346–53.
- Lacefield JC, von Ramm OT. Comparison of contrast in backscatter and angular scatter ultrasonic images. Proceedings of the IEEE Ultrasonics Symposium. 1996 Dec 1;2:1469–72.
- Bashford GR, Von Ramm OT. Ultrasound three-dimensional velocity measurements by feature tracking. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 1996 Dec 1;43(3):376–84.
- Stetten GD, Caines MS, Ohazama CJ, Ramm OT. Towards the volumetricardiogram: volume determination of cardiac chambers using 3D matrix-array ultrasound. Proceedings of SPIE - The International Society for Optical Engineering. 1995 Dec 1;2432:185–96.
- Stetten GD, Caines MS, Ramm OT. Flow integration transform: detecting shapes in matrix-array 3D ultrasound data. Proceedings of SPIE - The International Society for Optical Engineering. 1995 Dec 1;2424:242–52.
- Bashford GR, von Ramm OT. Speckle structure in three dimensions. The Journal of the Acoustical Society of America. 1995 Jul;98(1):35–42.
- Phillips PJ, Kadi AP, Von Ramm OT. Feasibility study for a two-dimensional diagnostic ultrasound velocity mapping system. Ultrasound in medicine & biology. 1995 Jan;21(2):217–29.
- Robinson MT, von Ramm OT. Real-Time Angular Scatter Imaging System for Improved Tissue Contrast in Diagnostic Ultrasound Images. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. 1994 Jan 1;41(1):44–52.
- Phillips PJ, von Ramm OT, Swartz JC, Guenther BD. Optical transducer for reception of ultrasonic waves. The Journal of the Acoustical Society of America. 1993 Feb;93(2):1182–91.
- Pilkington TC, Ideker RE, Ramm OTV. National Science Foundation/Engineering Research Center for emerging cardiovascular technologies. Proceedings of the IEEE. 1993;81(1):79–94.
- Smith SW, Trahey GE, von Ramm OT. Two-dimensional arrays for medical ultrasound. Ultrasonic imaging. 1992 Jul;14(3):213–33.
- von Ramm OT, Smith SW, Pavy HR. High-speed ultrasound volumetric imaging system. II. Parallel processing and image display. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 1991 Jan;38(2):109–15.
- Pavy HG, W. Smith S, von Ramm OT. Improved real time volumetric ultrasonic imaging system. Proceedings of SPIE - The International Society for Optical Engineering. 1991 Jan 1;1443:54–61.
- Robinson MT, Von Ramm OT. Real-time angular scatter imaging system. In: Proceedings - IEEE Ultrasonics Symposium. 1991. p. 1229–33.
- Smith SW, Pavy HR, von Ramm OT. High-speed ultrasound volumetric imaging system. I. Transducer design and beam steering. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 1991 Jan;38(2):100–8.
- Smith SW, Trahey GE, Von Ramm OT. Two-dimensional arrays for medical ultrasound. In: Proceedings - IEEE Ultrasonics Symposium. 1991. p. 625–8.
- Sheikh K, Smith SW, von Ramm O, Kisslo J. Real-time, three-dimensional echocardiography: feasibility and initial use. Echocardiography. 1991 Jan;8(1):119–25.
- von Ramm O, Castellucci J. Real-time 3D ultrasonic data acquistion. Proceedings of the Annual Conference on Engineering in Medicine and Biology. 1990 Dec 1;(pt 2):668–9.
- von Ramm OT, Smith SW. Real time volumetric ultrasound imaging system. Journal of digital imaging. 1990 Nov;3(4):261–6.
- Von Ramm OT, Smith SW. Real time volumetric ultrasound imaging system. Proceedings of SPIE - The International Society for Optical Engineering. 1990 Jul 1;1231:15–22.
- Smith SW, von Ramm OT. Laboratory evaluation of the Maltese cross processor: Speckle reduction for circular transducers. Ultrasonics Symposium Proceedings. 1989 Dec 1;2:853–7.
- Trahey GE, Hubbard SM, von Ramm OT. Angle independent ultrasonic blood flow detection by frame-to-frame correlation of B-mode images. Ultrasonics. 1988 Sep;26(5):271–6.
- Smith SW, von Ramm OT. The Maltese cross processor: speckle reduction for circular transducers. Ultrasonic imaging. 1988 Jul;10(3):153–70.
- Skorton DJ, Collins SM, Greenleaf JF, Meltzer RS, O’Brien WD, Schnittger I, et al. Ultrasound bioeffects and regulatory issues: an introduction for the echocardiographer. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography. 1988 May;1(3):240–51.
- Carroll BA, von Ramm OT. Fundamentals of current doppler technology. Ultrasound Quarterly. 1988 Jan 1;6(4):275–98.
- Trahey GE, Allison JW, Hubbard SM, von Ramm OT. MEASUREMENT OF LOCAL SPECKLE PATTERN DISPLACEMENT TO TRACK BLOOD FLOW IN TWO DIMENSIONS. Ultrasonics Symposium Proceedings. 1987 Dec 1;957–61.
- Trahey GE, Allison JW, von Ramm OT. Angle independent ultrasonic detection of blood flow. IEEE transactions on bio-medical engineering. 1987 Dec;34(12):965–7.
- Trahey GE, Allison JW, Smith SW, Von Ramm OT. Speckle reduction achievable by spatial compounding and frequency compounding: Experimental results and implications for target detectability. Proceedings of SPIE - The International Society for Optical Engineering. 1987 Sep 10;768:185–92.
- Trahey GE, Smith SW, Carroll BA, von Ramm OT. SPECKLE SNR VS. LATERAL RESOLUTION IN ULTRASOUND IMAGING: WHAT'S THE TRADEOFF? Ultrasonics Symposium Proceedings. 1986 Dec 1;811–3.
- Trahey GE, Allison JW, Smith SW, von Ramm OT. A quantitative approach to speckle reduction via frequency compounding. Ultrasonic imaging. 1986 Jul;8(3):151–64.
- Snyder JE, Kisslo J, von Ramm O. Real-time orthogonal mode scanning of the heart. I. System design. J Am Coll Cardiol. 1986 Jun;7(6):1279–85.
- Smith SW, Trahey GE, von Ramm OT. Phased array ultrasound imaging through planar tissue layers. Ultrasound in medicine & biology. 1986 Mar;12(3):229–43.
- Trahey GE, Allison JW, Smith SW, von Ramm OT. SPECKLE PATTERN CHANGES WITH VARYING ACOUSTIC FREQUENCY: EXPERIMENTAL MEASUREMENT AND IMPLICATIONS FOR FREQUENCY COMPOUNDING. Ultrasonics Symposium Proceedings. 1986 Jan 1;815–8.
- Trahey GE, Smith SW, von Ramm OT. Speckle reduction in medical ultrasound via spatial compounding. Proc SPIE - Int Soc Opt Eng (USA). 1986;626:290–300.
- Trahey GE, Smith SW, von Ramm OT. Speckle pattern correlation with lateral aperture translation: experimental results and implications for spatial compounding. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. 1986 Jan;33(3):257–64.
- Shattuck DP, Weinshenker MD, Smith SW, von Ramm OT. Explososcan: A parallel processing technique for high speed ultrasound imaging with linear phased arrays. Proceedings of SPIE - The International Society for Optical Engineering. 1985 Jun 11;535:247–60.
- Shattuck DP, Weinshenker MD, Smith SW, von Ramm OT. Explososcan: a parallel processing technique for high speed ultrasound imaging with linear phased arrays. The Journal of the Acoustical Society of America. 1984 Apr;75(4):1273–82.
- Teague SM, von Ramm OT, Kisslo JA. Pulsed Doppler spectral analysis of bounded fluid jets. Ultrasound Med Biol. 1984;10(4):435–41.
- von Ramm OT, Smith SW. Beam steering with linear arrays. IEEE transactions on bio-medical engineering. 1983 Aug;30(8):438–52.
- Von Ramm OT, Smith SW. Beam steering with linear arrays. IEEE Trans Biomed Eng (USA). 1983;BME-30(8):438–52.
- Magnin PA, von Ramm OT, Thurstone FL. Frequency compounding for speckle contrast reduction in phased array images. Ultrasonic imaging. 1982 Jul;4(3):267–81.
- Shattuck DP, von Ramm OT. Compound scanning with a phased array. Ultrasonic imaging. 1982 Apr;4(2):93–107.
- Magnin PA, Thurstone FL, von Ramm OT. ANOMALOUS QUANTIZATION ERROR LOBES IN PHASED ARRAY IMAGES. Acoustical Imaging: Proceedings of the International Symposium. 1982 Jan 1;11:491–503.
- Magnin PA, Stewart JA, Myers S, von Ramm O, Kisslo JA. Combined doppler and phased-array echocardiographic estimation of cardiac output. Circulation. 1981 Feb;63(2):388–92.
- Magnin PA, Von Ramm OT, Thurstone FL. Delay Quantization Error in Phased Array Images. IEEE Transactions on Sonics and Ultrasonics. 1981 Jan 1;28(5):305–10.
- Magnin PA, Ramm OTV, Thurstone FL. DELAY QUANTIZATION ERROR IN PHASED ARRAY IMAGES. IEEE transactions on sonics and ultrasonics. 1981;SU-28(5):305–10.
- Magnin PA, von Ramm OT. ON GREATER VISUALIZATION OF MYOCARDIUM. 1980 Dec 1;132.
- Morgan CL, Trought WS, von Ramm OT, Thurstone FL. Abdominal and obstetric applications of a dynamically focused phased array real time ultrasound system. Clinical radiology. 1980 May;31(3):277–86.
- von Ramm OT, Smith SW. Prospects and limitations of diagnostic ultrasound. Proceedings of SPIE - The International Society for Optical Engineering. 1979 Dec 26;206:6–18.
- von Ramm OT, Miller-Jones S, Butts HB, Smith SW. ADAPTIVE ULTRASOUND CEPHALIC IMAGING SYSTEM. 1979 Dec 1;66.
- von Ramm OT, Shattuck DP, Bauer BJ, Thurstone FL. PHASE ARRAY COMPOUND SCANNING. 1979 Dec 1;68.
- Smith SW, Haran ME. Angular Response of Piezoelectric Elements in Phased Array Ultrasound Scanners. IEEE Transactions on Sonics and Ultrasonics. 1979 Jan 1;26(3):185–90.
- Smith SW, von Ramm OT, Haran ME, Thurstone FL. ANGULAR RESPONSE OF PIEZOELECTRIC ELEMENTS IN PHASED ARRAY ULTRASOUND SCANNERS. IEEE Transactions on Sonics and Ultrasonics. 1979;SU-26(3):185–91.
- Morgan CL, Trought WS, Clark WM, Von Ramm OT, Thurstone FL. Principles and applications of a dynamically focused phased array real time ultrasound system. Journal of clinical ultrasound : JCU. 1978 Dec;6(6):385–91.
- Von Ramm OT. A Multiple Frequency Array for Improved Diagnostic Imaging. IEEE Transactions on Sonics and Ultrasonics. 1978 Jan 1;25(6):340–5.
- Kisslo JA, von Ramm OT, Thurstone FL. Techniques for real-time two-dimensional echocardiography. Cardiovasc Clin. 1978;9(2):21–38.
- Smith SW, von Ramm OT, Kisslo JA, Thurstone FL. Real time ultrasound tomography of the adult brain. Stroke. 1978;9(2):117–22.
- Kisslo JA, vonRamm OT, Thurstone FL. Dynamic cardiac imaging using a focused, phased-array ultrasound system. Am J Med. 1977 Jul;63(1):61–8.
- Kisslo JA, vonRamm OT, Thurstone FL. Clinical results of real-time ultrasonic scanning of the heart using a phased array system. Yale J Biol Med. 1977;50(4):355–65.
- Kisslo JA, Robertson D, Gilbert BW, von Ramm O, Behar VS. A comparison of real-time, two dimensional echocardiography and cineangiography in detecting left ventricular asynergy. Circulation. 1977 Jan;55(1):134–41.
- Gilbert BW, Schatz RA, VonRamm OT, Behar VS, Kisslo JA. Mitral valve prolapse. Two-dimensional echocardiographic and angiographic correlation. Circulation. 1976 Nov;54(5):716–23.
- Kisslo J, Von Ramm OT, Haney R, Jones R, Juk SS, Behar VS. Echocardiographic evaluation of tricuspid valve endocarditis: an M mode and two dimensional study. Am J Cardiol. 1976 Oct;38(4):502–7.
- von Ramm OT, Smith SW, Thurstone FL. Gray scale imaging with complex tgc and transducer arrays. Proceedings of SPIE - The International Society for Optical Engineering. 1976 Mar 25;70:266–70.
- Kisslo J, Von Ramm O, Thurstone FL. Dynamic cardiac imaging using a phased-array transducer system. Proceedings of SPIE - The International Society for Optical Engineering. 1976 Mar 11;72:45–52.
- Kisslo J, vonRamm OT, Thurstone FL. Cardiac imaging using a phased array ultrasound system. II. Clinical technique and application. Circulation. 1976 Feb;53(2):262–7.
- vonRamm OT, Thurstone FL. Cardiac imaging using a phased array ultrasound system. I. System design. Circulation. 1976 Feb;53(2):258–62.
- Von Ramm OT, Thurstone FL, Kisslo J. Real time two-dimensional echocardiography. In: Proceedings of SPIE - The International Society for Optical Engineering. 1975. p. 93–5.
- von Ramm OT, Thurstone FL, Kisslo J. CARDIOVASCULAR DIAGNOSIS WITH REAL TIME ULTRASOUND IMAGING. Acoust Hologr. 1975 Jan 1;6:91–102.
- Kisslo J, von Ramm O, Thurstone FL. DYNAMIC CARDIAC IMAGING USING A PHASED-ARRAY TRANSDUCER SYSTEM. SPIE Semin Proc. 1975 Jan 1;72:45–9.
- Kisslo J, Von Ramm O, Thurstone FL. Dynamic cardiac imaging using a phased array transducer system. PROCSOCPHOTO-OPTINSTRENGIN. 1975 Jan 1;Vol.72:45–9.
- Thurstone FL, von Ramm OT. ACOUSTICAL IMAGING WITH A LINEAR PHASED ARRAY. 1975 Jan 1;73–4.
- Kisslo J, Von Ramm OT, Thurstone FL. A phased array ultrasound system for cardiac imaging. EXCERPTA MEDICA, ICS NO 363. 1975 Jan 1;67–74.
- Phillips DJ, Smith SW, von Ramm OT, Thurstone FL. SAMPLED APERTURE TECHNIQUES APPLIED TO B-MODE ECHOENCEPHALOGRAPHY. Acoust Hologr. 1975 Jan 1;6:103–20.
- Thurstone FL, von Ramm OT. NEW ULTRASOUND IMAGING TECHNIQUE EMPLOYING TWO-DIMENSIONAL ELECTRONIC BEAM STEERING. 1974 Dec 1;
- von Ramm OT, Thurstone FL, Kisslo J. REAL TIME TWO-DIMENSIONAL ECHOCARDIOGRAPHY. SPIE Semin Proc. 1974 Jan 1;47:93–5.
- Thurstone FL, von Ramm OT. NEW ULTRASOUND IMAGING TECHNIQUE EMPLOYING TWO-DIMENSIONAL ELECTRONIC BEAM STEERING. In 1974.
- Thurstone FL, von Ramm OT. NEW ULTRASOUND IMAGING TECHNIQUE EMPLOYING TWO-DIMENSIONAL ELECTRONIC BEAM STEERING. 1974 Jan 1;
- Booth N, Saltzer B, Fitspatrick GL, Vilkomerson D, Wang K, Wade G, et al. ACOUSTICAL HOLOGRAPHY, VOLUME 4. Acoust Hologr. 1972 Jan 1;4.
- Kunov H, Von Ramm O. Coherent optical processing of optical data. Nouvelle Revue d’Optique Appliquée. 1970 Dec 1;1(2):22.
- BROWN MR, VON RAMM OT, STASKO RR. THREE TECHNIQUES OF SPECTRAL ANALYSIS IN ELECTROCARDIOGRAMS. 1970 Jan 1;
In The News
- The Pioneers of 3D Ultrasound (Apr 1, 2018 | Duke Biomedical Engineering)
- Thurstone Medical Imaging Fellowship Awarded to Duke BME PhD Candidate (Nov 13, 2013 | Duke University Pratt School of Engineering)