Amy Susanne Gladfelter

Cell Biology

Duke Health Distinguished Professor of Cell Biology and Biomedical Engineering

Amy Susanne Gladfelter Profile Photo

Education

Ph.D. Duke University, 2001

Trainings & Certifications

Assistant Professor Biological Sciences, Dartmouth College 2006 - 2012 (2006 - 2012) Dartmouth College
Adjunct Associate Scientist, Woods Hole Oceanographic Institution, MARINE BIOLOGICAL LABORATORY 2012 - 2017 (2012 - 2017) Woods Hole Oceanographic Institution
Associate Professor Biological Sciences, Dartmouth College 2012 - 2016 (2012 - 2016) Dartmouth College
Fellow, Woods Hole Oceanographic Institution, MARINE BIOLOGICAL LABORATORY 2017 - 2028 (2017 - 2028) Woods Hole Oceanographic Institution
Associate Chair, University of North Carolina, Chapel Hill, BIOLOGY 2017 - 2022 (2017 - 2022) University of North Carolina, Chapel Hill
Professor, University of North Carolina, Chapel Hill, BIOLOGY 2020 - 2023 (2020 - 2023) University of North Carolina, Chapel Hill

Positions

Duke Health Distinguished Professor of Cell Biology and Biomedical Engineering
Professor of Cell Biology
Professor of Biomedical Engineering
Professor in Obstetrics and Gynecology
Member of the Duke Cancer Institute

Awards, Honors, and Distinctions

American Academy of Arts and Sciences Member/Fellow. American Academy of Arts and Sciences. 2023
American Academy of Microbiology Member/Fellow. American Academy of Microbiology . 2023
HHMI Investigator semi-finalist. Howard Hughes Medical Institute (HHMI). 2021
AAAS Fellow. American Association for the Advancement of Science. 2021
Excellence in Basic Science Mentoring Award. School of Medicine, UNC Chapel Hill . 2020
HHMI Investigator semi-finalist. Howard Hughes Medical Institute (HHMI). 2018
Howard Hughes Medical Institute (HHMI) Faculty Scholar. Howard Hughes Medical Institute (HHMI). 2016
Women in Cell Biology Mid-Career Award for Excellence in Research.. American Society of Cell Biology. 2015
Nikon Fellow. Marine Biological Laboratory, Woods Hole. 2013
Douglas C. Floren Fellow. Dartmouth College . 2012
Karen E. Wetterhahn Memorial Award for Distinguished Creative and Scholarly Achievement. Dartmouth College . 2012
Basil Ou2019Connor Scholar. March of Dimes. 2008

Courses Taught

CELLBIO 493: Research Independent Study
BIOCHEM 700: Graduate Training Internship

Publications

Curtis BN, Vogt EJD, Ekena JL, Edelmaier C, Gladfelter AS. Lipid packing and local geometry influence septin curvature sensing. J Cell Biol. 2026 Jan 5;225(1).
Crocker AW, Petrucco CA, Guan K, Wirshing ACE, Ekena JL, Lew DJ, et al. Negative feedback equalizes polarity sites in a multi-budding yeast. Curr Biol. 2025 Nov 17;35(22):5666u20137.
Petrucco CA, Crocker AW, Wirshing ACE, Colarusso AV, Waarts M, Gladfelter AS, et al. Mechanisms of nuclear segregation in a multinucleate multibudding yeast. J Cell Biol. 2025 Nov 3;224(11).
Zahn G, Amend A, Gladfelter A. Mycology: The rising tide of marine fungal research. Curr Biol. 2025 Oct 20;35(20):R946u20138.
Gladfelter A. Amy Gladfelter. Curr Biol. 2025 Oct 6;35(19):R901u20132.
Alberti S, Arosio P, Best RB, Boeynaems S, Cai D, Collepardo-Guevara R, et al. Current practices in the study of biomolecular condensates: a community comment. Nat Commun. 2025 Aug 19;16(1):7730.
Snead WT, Skillicorn MK, Shrinivas K, Gladfelter AS. Immiscible proteins compete for RNA binding to order condensate layers. Proc Natl Acad Sci U S A. 2025 Aug 12;122(32):e2504778122.
Vogt EJD, Seim I, Snead WT, Curtis BN, Gladfelter AS. Cooperativity in septin polymerization is tunable by ionic strength and membrane adsorption. Biophys J. 2025 Aug 7;
Crocker AW, Petrucco CA, Guan K, Wirshing ACE, Ekena JL, Lew DJ, et al. Negative feedback equalizes polarity sites in a multi-budding yeast. Curr Biol. 2025 Jul 7;35(13):3022-3034.e4.
Keenen MM, Jalihal A, Gladfelter AS. Achieving multifunctionality in a single, tissue-sized syncytiotrophoblast cell in humans. Placenta. 2025 Jun 18;
Jalihal AP, Gladfelter AS. Fungal syncytia. Curr Biol. 2025 Jun 9;35(11):R490u20135.
Colarusso AV, Williams AM, Gladfelter AS, Wirshing ACE, Lew DJ. Optimized vectors for genetic engineering of Aureobasidium pullulans. Mol Biol Cell. 2025 Jun 1;36(6):mr5.
Goodchild JA, Curtis BN, Pan Y, Jiang Y, Jiao F, Gladfelter AS, et al. Septin higher-order structure on yeast membranes in vitro. Nat Commun. 2025 May 30;16(1):5055.
Edelmaier CJ, Klawa SJ, Mofidi SM, Wang Q, Bhonge S, Vogt EJD, et al. Charge distribution and helicity tune the binding of septin's amphipathic helix domain to membranes. Biophys J. 2025 Apr 15;124(8):1298u2013312.
Bettencourt-Dias M, Gladfelter A, Dey G, Reck-Peterson SL. Cell biology meets climate resilience - a call to action. J Cell Sci. 2025 Mar 15;138(6).
Zhang V, Gladfelter AS, Roden CA. Biomolecular condensates: It was RNA all along!. Mol Cell. 2025 Feb 6;85(3):461u20133.
Curtis BN, Gladfelter AS. Drivers of Morphogenesis: Curvature Sensor Self-Assembly at the Membrane. Cold Spring Harb Perspect Biol. 2024 Dec 2;16(12).
Jalihal AP, Geisterfer ZM, Gladfelter AS. RNAs kiss and translate in germ granules. Nat Cell Biol. 2024 Nov;26(11):1828u20139.
Hamilton GE, Wadkovsky KN, Gladfelter AS. A single septin from a polyextremotolerant yeast recapitulates many canonical functions of septin hetero-oligomers. Mol Biol Cell. 2024 Oct 1;35(10):ar132.
Roden CA, Gladfelter AS. Experimental Considerations for the Evaluation of Viral Biomolecular Condensates. Annu Rev Virol. 2024 Sep;11(1):105u201324.
Stormo BM, McLaughlin GA, Jalihal AP, Frederick LK, Cole SJ, Seim I, et al. Intrinsically disordered sequences can tune fungal growth and the cell cycle for specific temperatures. Curr Biol. 2024 Aug 19;34(16):3722-3734.e7.
Mayer A, Li J, McLaughlin G, Gladfelter A, Roper M. Mitigating transcription noise via protein sharing in syncytial cells. Biophys J. 2024 Apr 16;123(8):968u201378.
Petrucco CA, Crocker AW, Du2019Alessandro A, Medina EM, Gorman O, McNeill J, et al. Tools for live-cell imaging of cytoskeletal and nuclear behavior in the unconventional yeast, Aureobasidium pullulans. Mol Biol Cell. 2024 Apr 1;35(4):br10.
Mayer A, McLaughlin G, Gladfelter A, Glass NL, Mela A, Roper M. Syncytial Assembly Lines: Consequences of Multinucleate Cellular Compartments for Fungal Protein Synthesis. Results Probl Cell Differ. 2024;71:159u201383.
Lin AZ, Ruff KM, Dar F, Jalihal A, King MR, Lalmansingh JM, et al. Dynamical control enables the formation of demixed biomolecular condensates. Nat Commun. 2023 Nov 24;14(1):7678.
Steinbach RM, El Baidouri F, Mitchison-Field LMY, Lim FY, Ekena J, Vogt EJD, et al. Malassezia is widespread and has undescribed diversity in the marine environment. Fungal Ecology. 2023 Oct 1;65.
Kakizaki T, Abe H, Kotouge Y, Matsubuchi M, Sugou M, Honma C, et al. Live-cell imaging of septins and cell polarity proteins in the growing dikaryotic vegetative hypha of the model mushroom Coprinopsis cinerea. Sci Rep. 2023 Jun 22;13(1):10132.
Cannon KS, Vargas-Muniz JM, Billington N, Seim I, Ekena J, Sellers JR, et al. A gene duplication of a septin reveals a developmentally regulated filament length control mechanism. J Cell Biol. 2023 Mar 6;222(3).
Mayer AJ, Roper M, Gladfelter AS, McLaughlin G. The role of RNA condensation in reducing gene expression noise. Biophysical journal. 2023 Feb 10;122(3S1):415a-416a.
Seim I, Graham AJ, Mathijssen A, Gladfelter AS. RNA structure controls composition and network dynamics of condensates. Biophysical journal. 2023 Feb 10;122(3S1).
Shi W, Cannon KS, Curtis BN, Edelmaier C, Gladfelter AS, Nazockdast E. Curvature sensing as an emergent property of multiscale assembly of septins. Proc Natl Acad Sci U S A. 2023 Feb 7;120(6):e2208253120.
Jacobs KC, Gladfelter AS, Lew DJ. Targeted secretion: Myosin V delivers vesicles through formin condensates. Curr Biol. 2022 Nov 7;32(21):R1228u201331.
Roden CA, Dai Y, Giannetti CA, Seim I, Lee M, Sealfon R, et al. Double-stranded RNA drives SARS-CoV-2 nucleocapsid protein to undergo phase separation at specific temperatures. Nucleic Acids Res. 2022 Aug 12;50(14):8168u201392.
Bartholomai BM, Gladfelter AS, Loros JJ, Dunlap JC. PRD-2 mediates clock-regulated perinuclear localization of clock gene RNAs within the circadian cycle of Neurospora. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2203078119.
Curtis BN, Vogt EJD, Cannon KS, Gladfelter AS. Reconstitution of Septin Assembly at Membranes to Study Biophysical Properties and Functions. J Vis Exp. 2022 Jul 28;(185).
Seim I, Roden CA, Gladfelter AS. Role of spatial patterning of N-protein interactions in SARS-CoV-2 genome packaging. Biophys J. 2022 Apr 19;121(8):1580.
Snead WT, Jalihal AP, Gerbich TM, Seim I, Hu Z, Gladfelter AS. Membrane surfaces regulate assembly of ribonucleoprotein condensates. Nat Cell Biol. 2022 Apr;24(4):461u201370.
Seim I, Posey AE, Snead WT, Stormo BM, Klotsa D, Pappu RV, et al. Dilute phase oligomerization can oppose phase separation and modulate material properties of a ribonucleoprotein condensate. Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2120799119.
Roden CA, Gladfelter AS. Design considerations for analyzing protein translation regulation by condensates. RNA. 2022 Jan;28(1):88u201396.
Hiiragi T, Gladfelter AS, Miguel-Aliaga I, Coller HA, Lau OS, McBride HM, et al. 20 years of Developmental Cell: Looking forward. Dev Cell. 2021 Dec 6;56(23):3185u201391.
Bartholomai BM, Gladfelter AS, Loros JJ, Dunlap JC. Quantitative single molecule RNA-FISH and RNase-free cell wall digestion in Neurospora crassa. Fungal Genet Biol. 2021 Nov;156:103615.
El Baidouri F, Zalar P, James TY, Gladfelter AS, Amend AS. Evolution and Physiology of Amphibious Yeasts. Vol. 75. 2021.
Woods BL, Cannon KS, Vogt EJD, Crutchley JM, Gladfelter AS. Interplay of septin amphipathic helices in sensing membrane-curvature and filament bundling. Mol Biol Cell. 2021 Oct 1;32(20):br5.
Snead WT, Gladfelter AS. Getting droplets into shape. Science. 2021 Sep 10;373(6560):1198u20139.
Seim I, Roden CA, Gladfelter AS. Role of spatial patterning of N-protein interactions in SARS-CoV-2 genome packaging. Biophys J. 2021 Jul 20;120(14):2771u201384.
Lenne P-F, Munro E, Heemskerk I, Warmflash A, Bocanegra-Moreno L, Kishi K, et al. Roadmap for the multiscale coupling of biochemical and mechanical signals during development. Phys Biol. 2021 Apr 14;18(4).
Mitchison-Field LMY, Gladfelter AS. Culturing and Multiplexed Time-Lapse Imaging of Fungal Isolates from Marine and Coastal Environments. Curr Protoc. 2021 Apr;1(4):e94.
Gerbich TM, Gladfelter AS. Moving beyond disease to function: Physiological roles for polyglutamine-rich sequences in cell decisions. Curr Opin Cell Biol. 2021 Apr;69:120u20136.
Roden C, Gladfelter AS. RNA contributions to the form and function of biomolecular condensates. Nat Rev Mol Cell Biol. 2021 Mar;22(3):183u201395.
Yu H, Lu S, Gasior K, Singh D, Vazquez-Sanchez S, Tapia O, et al. HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells. Science. 2021 Feb 5;371(6529).
Woods BL, Gladfelter AS. The state of the septin cytoskeleton from assembly to function. Curr Opin Cell Biol. 2021 Feb;68:105u201312.
Iserman C, Roden CA, Boerneke MA, Sealfon RSG, McLaughlin GA, Jungreis I, et al. Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid. Mol Cell. 2020 Dec 17;80(6):1078-1091.e6.
Selbmann L, Benku0151 Z, Coleine C, de Hoog S, Donati C, Druzhinina I, et al. Shed light in the dark lineages of the fungal tree of lifeu2014stres. Life. 2020 Dec 1;10(12):1u201313.
Gasior K, Forest MG, Gladfelter AS, Newby JM. Modeling the Mechanisms by Which Coexisting Biomolecular RNA-Protein Condensates Form. Bull Math Biol. 2020 Nov 24;82(12):153.
Jiao F, Cannon KS, Lin Y-C, Gladfelter AS, Scheuring S. The hierarchical assembly of septins revealed by high-speed AFM. Nat Commun. 2020 Oct 8;11(1):5062.
Gerbich TM, McLaughlin GA, Cassidy K, Gerber S, Adalsteinsson D, Gladfelter AS. Phosphoregulation provides specificity to biomolecular condensates in the cell cycle and cell polarity. J Cell Biol. 2020 Jul 6;219(7).
McLaughlin GA, Langdon EM, Crutchley JM, Holt LJ, Forest MG, Newby JM, et al. Spatial heterogeneity of the cytosol revealed by machine learning-based 3D particle tracking. Mol Biol Cell. 2020 Jul 1;31(14):1498u2013511.
Smith JA, Curry EG, Blue RE, Roden C, Dundon SER, Rodru00edguez-Vargas A, et al. FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells. J Cell Biol. 2020 Apr 6;219(4).
Johnson CR, Steingesser MG, Weems AD, Khan A, Gladfelter A, Bertin A, et al. Guanidine hydrochloride reactivates an ancient septin hetero-oligomer assembly pathway in budding yeast. Elife. 2020 Jan 28;9.
Mitchison-Field LMY, Vargas-Muu00f1iz JM, Stormo BM, Vogt EJD, Van Dierdonck S, Pelletier JF, et al. Unconventional Cell Division Cycles from Marine-Derived Yeasts. Curr Biol. 2019 Oct 21;29(20):3439-3456.e5.
Snead WT, Gladfelter AS. The Control Centers of Biomolecular Phase Separation: How Membrane Surfaces, PTMs, and Active Processes Regulate Condensation. Mol Cell. 2019 Oct 17;76(2):295u2013305.
Cannon KS, Woods BL, Crutchley JM, Gladfelter AS. An amphipathic helix enables septins to sense micrometer-scale membrane curvature. J Cell Biol. 2019 Apr 1;218(4):1128u201337.
Li H, Saucedo-Cuevas L, Yuan L, Ross D, Johansen A, Sands D, et al. Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors. Neuron. 2019 Mar 20;101(6):1089-1098.e4.
Gladfelter AS, James TY, Amend AS. Marine fungi. Curr Biol. 2019 Mar 18;29(6):R191u20135.
Amend A, Burgaud G, Cunliffe M, Edgcomb VP, Ettinger CL, Gutiu00e9rrez MH, et al. Fungi in the Marine Environment: Open Questions and Unsolved Problems. mBio. 2019 Mar 5;10(2).
Alberti S, Gladfelter A, Mittag T. Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates. Cell. 2019 Jan 24;176(3):419u201334.
Gasior K, Zhao J, McLaughlin G, Forest MG, Gladfelter AS, Newby J. Partial demixing of RNA-protein complexes leads to intradroplet patterning in phase-separated biological condensates. Phys Rev E. 2019 Jan;99(1u20131):012411.
Langdon EM, Gladfelter AS. A New Lens for RNA Localization: Liquid-Liquid Phase Separation. Vol. 72. 2018.
Garcia HG, Benzinger D, Rullan M, Milias-Argeitis A, Khammash M, Deutschbauer AM, et al. Principles of Systems Biology, No. 30. Cell Syst. 2018 Jul 25;7(1):1u20132.
Langdon EM, Qiu Y, Ghanbari Niaki A, McLaughlin GA, Weidmann CA, Gerbich TM, et al. mRNA structure determines specificity of a polyQ-driven phase separation. Science. 2018 May 25;360(6391):922u20137.
Fadero TC, Gerbich TM, Rana K, Suzuki A, DiSalvo M, Schaefer KN, et al. LITE microscopy: Tilted light-sheet excitation of model organisms offers high resolution and low photobleaching. J Cell Biol. 2018 May 7;217(5):1869u201382.
Khan A, Newby J, Gladfelter AS. Control of septin filament flexibility and bundling by subunit composition and nucleotide interactions. Mol Biol Cell. 2018 Mar 15;29(6):702u201312.
Langdon EM, Gladfelter AS. Probing RNA Structure in Liquid-Liquid Phase Separation Using SHAPE-MaP. In 2018. p. 67u201379.
Cannon KS, Woods BL, Gladfelter AS. The Unsolved Problem of How Cells Sense Micron-Scale Curvature. Trends Biochem Sci. 2017 Dec;42(12):961u201376.
Smith JA, Gladfelter AS. Lessons from Yeast on How to Avoid Stress Eating. Dev Cell. 2017 Oct 9;43(1):3u20135.
Gladfelter AS, Peifer M. What your PI forgot to tell you: why you actually might want a job running a research lab. Mol Biol Cell. 2017 Jul 1;28(13):1724u20137.
Russell JJ, Theriot JA, Sood P, Marshall WF, Landweber LF, Fritz-Laylin L, et al. Non-model model organisms. BMC Biol. 2017 Jun 29;15(1):55.
McQuilken M, Jentzsch MS, Verma A, Mehta SB, Oldenbourg R, Gladfelter AS. Analysis of septin reorganization at cytokinesis using polarized fluorescence microscopy. Frontiers in Cell and Developmental Biology. 2017 May 3;5(MAY).
Bridges AA, Gladfelter AS. Septin complexes assemble during a kinetic window of opportunity. Cell Cycle. 2016 Nov;15(21):2858u20139.
Mehta SB, McQuilken M, La Riviere PJ, Occhipinti P, Verma A, Oldenbourg R, et al. Dissection of molecular assembly dynamics by tracking orientation and position of single molecules in live cells. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):E6352u201361.
Dundon SER, Chang S-S, Kumar A, Occhipinti P, Shroff H, Roper M, et al. Clustered nuclei maintain autonomy and nucleocytoplasmic ratio control in a syncytium. Mol Biol Cell. 2016 Jul 1;27(13):2000u20137.
Bridges AA, Jentzsch MS, Oakes PW, Occhipinti P, Gladfelter AS. Micron-scale plasma membrane curvature is recognized by the septin cytoskeleton. J Cell Biol. 2016 Apr 11;213(1):23u201332.
Lee C, Roberts SE, Gladfelter AS. Quantitative spatial analysis of transcripts in multinucleate cells using single-molecule FISH. Methods. 2016 Apr 1;98:124u201333.
Bridges AA, Gladfelter AS. In vitro reconstitution of septin assemblies on supported lipid bilayers. Methods Cell Biol. 2016;136:57u201371.
Roberts SE, Gladfelter AS. Nuclear autonomy in multinucleate fungi. Curr Opin Microbiol. 2015 Dec;28:60u20135.
Gladfelter AS. How nontraditional model systems can save us. Mol Biol Cell. 2015 Nov 1;26(21):3687u20139.
Zhang H, Elbaum-Garfinkle S, Langdon EM, Taylor N, Occhipinti P, Bridges AA, et al. RNA Controls PolyQ Protein Phase Transitions. Mol Cell. 2015 Oct 15;60(2):220u201330.
Roper M, Lee C, Hickey PC, Gladfelter AS. Life as a moving fluid: fate of cytoplasmic macromolecules in dynamic fungal syncytia. Curr Opin Microbiol. 2015 Aug;26:116u201322.
Hogan DA, Gladfelter AS. Editorial overview: host-microbe interactions: fungi: heterogeneity in fungal cells, populations, and communities. Curr Opin Microbiol. 2015 Aug;26:viiu2013ix.
Bridges AA, Gladfelter AS. Septin Form and Function at the Cell Cortex. J Biol Chem. 2015 Jul 10;290(28):17173u201380.
Kaplan C, Jing B, Winterflood CM, Bridges AA, Occhipinti P, Schmied J, et al. Absolute Arrangement of Subunits in Cytoskeletal Septin Filaments in Cells Measured by Fluorescence Microscopy. Nano Lett. 2015 Jun 10;15(6):3859u201364.
McQuilken M, Mehta SB, Verma A, Harris G, Oldenbourg R, Gladfelter AS. Polarized Fluorescence Microscopy to Study Cytoskeleton Assembly and Organization in Live Cells. Curr Protoc Cell Biol. 2015 Jun 1;67:4.29.1-4.29.13.
Bezanilla M, Gladfelter AS, Kovar DR, Lee W-L. Cytoskeletal dynamics: a view from the membrane. J Cell Biol. 2015 May 11;209(3):329u201337.
Dasgupta A, Chen C-H, Lee C, Gladfelter AS, Dunlap JC, Loros JJ. Biological Significance of Photoreceptor Photocycle Length: VIVID Photocycle Governs the Dynamic VIVID-White Collar Complex Pool Mediating Photo-adaptation and Response to Changes in Light Intensity. PLoS Genet. 2015 May;11(5):e1005215.
Abrahamsson S, McQuilken M, Mehta SB, Verma A, Larsch J, Ilic R, et al. MultiFocus Polarization Microscope (MF-PolScope) for 3D polarization imaging of up to 25 focal planes simultaneously. Opt Express. 2015 Mar 23;23(6):7734u201354.
Anderson CA, Roberts S, Zhang H, Kelly CM, Kendall A, Lee C, et al. Ploidy variation in multinucleate cells changes under stress. Mol Biol Cell. 2015 Mar 15;26(6):1129u201340.
Lee C, Occhipinti P, Gladfelter AS. PolyQ-dependent RNA-protein assemblies control symmetry breaking. J Cell Biol. 2015 Mar 2;208(5):533u201344.
Khan A, McQuilken M, Gladfelter AS. Septins and Generation of Asymmetries in Fungal Cells. Vol. 69. 2015.
Bridges AA, Gladfelter AS. Fungal pathogens are platforms for discovering novel and conserved septin properties. Curr Opin Microbiol. 2014 Aug;20:42u20138.
Gladfelter AS. Cytoskeleton: cirque du septins. Curr Biol. 2014 Jun 2;24(11):R526u20138.
Bridges AA, Zhang H, Mehta SB, Occhipinti P, Tani T, Gladfelter AS. Septin assemblies form by diffusion-driven annealing on membranes. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2146u201351.
Anderson CA, Eser U, Korndorf T, Borsuk ME, Skotheim JM, Gladfelter AS. Nuclear repulsion enables division autonomy in a single cytoplasm. Curr Biol. 2013 Oct 21;23(20):1999u20132010.
Lee C, Zhang H, Baker AE, Occhipinti P, Borsuk ME, Gladfelter AS. Protein aggregation behavior regulates cyclin transcript localization and cell-cycle control. Dev Cell. 2013 Jun 24;25(6):572u201384.
Meseroll RA, Occhipinti P, Gladfelter AS. Septin phosphorylation and coiled-coil domains function in cell and septin ring morphology in the filamentous fungus Ashbya gossypii. Eukaryot Cell. 2013 Feb;12(2):182u201393.
Meseroll RA, Howard L, Gladfelter AS. Septin ring size scaling and dynamics require the coiled-coil region of Shs1p. Mol Biol Cell. 2012 Sep;23(17):3391u2013406.
Gerstenberger JP, Occhipinti P, Gladfelter AS. Heterogeneity in mitochondrial morphology and membrane potential is independent of the nuclear division cycle in multinucleate fungal cells. Eukaryot Cell. 2012 Mar;11(3):353u201367.
Spiliotis ET, Gladfelter AS. Spatial guidance of cell asymmetry: septin GTPases show the way. Traffic. 2012 Feb;13(2):195u2013203.
Anker JF, Gladfelter AS. Axl2 integrates polarity establishment, maintenance, and environmental stress response in the filamentous fungus Ashbya gossypii. Eukaryot Cell. 2011 Dec;10(12):1679u201393.
DeMay BS, Noda N, Gladfelter AS, Oldenbourg R. Rapid and quantitative imaging of excitation polarized fluorescence reveals ordered septin dynamics in live yeast. Biophys J. 2011 Aug 17;101(4):985u201394.
DeMay BS, Bai X, Howard L, Occhipinti P, Meseroll RA, Spiliotis ET, et al. Septin filaments exhibit a dynamic, paired organization that is conserved from yeast to mammals. J Cell Biol. 2011 Jun 13;193(6):1065u201381.
Gladfelter AS. Guides to the final frontier of the cytoskeleton: septins in filamentous fungi. Curr Opin Microbiol. 2010 Dec;13(6):720u20136.
Chen C-H, DeMay BS, Gladfelter AS, Dunlap JC, Loros JJ. Physical interaction between VIVID and white collar complex regulates photoadaptation in Neurospora. Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16715u201320.
Nair DR, Du2019Ausilio CA, Occhipinti P, Borsuk ME, Gladfelter AS. A conserved Gu2081 regulatory circuit promotes asynchronous behavior of nuclei sharing a common cytoplasm. Cell Cycle. 2010 Sep 15;9(18):3771u20139.
Gladfelter A. Stuck in a checkpoint: A role for Ras deregulation in DNA damage checkpoint recovery. Cell Cycle. 2010 Sep 1;9(17):3398.
DeMay BS, Meseroll RA, Occhipinti P, Gladfelter AS. Cellular requirements for the small molecule forchlorfenuron to stabilize the septin cytoskeleton. Cytoskeleton (Hoboken). 2010 Jun;67(6):383u201399.
Gladfelter A, Berman J. Dancing genomes: fungal nuclear positioning. Nat Rev Microbiol. 2009 Dec;7(12):875u201386.
DeMay BS, Meseroll RA, Occhipinti P, Gladfelter AS. Regulation of distinct septin rings in a single cell by Elm1p and Gin4p kinases. Mol Biol Cell. 2009 Apr;20(8):2311u201326.
Gladfelter AS, Sudbery P. Septins in Four Model Fungal Systems: Diversity in Form and Function. In: Septins. 2008. p. 125u201346.
Sudbery PE, Gladfelter AS. Pathocycles. Fungal Genet Biol. 2008 Jan;45(1):1u20135.
Gladfelter AS, Montagna C. Seeking truth on Monte Verita. Workshop on the molecular biology and biochemistry of septins and septin function. In: EMBO Rep. 2007. p. 1120u20136.
Martyanov V, Elderon L, Gladfelter A, Nair DR, Gross RH. Identifying fungal regulatory motif patterns using SCOPE, an ensemble learning method motif finder. In: Proceedings of the 7th IEEE International Conference on Bioinformatics and Bioengineering Bibe. 2007. p. 1183u20137.
Hungerbuehler AK, Philippsen P, Gladfelter AS. Limited functional redundancy and oscillation of cyclins in multinucleated Ashbya gossypii fungal cells. Eukaryot Cell. 2007 Mar;6(3):473u201386.
Gladfelter AS, Sustreanu N, Hungerbuehler AK, Voegeli S, Galati V, Philippsen P. The anaphase-promoting complex/cyclosome is required for anaphase progression in multinucleated Ashbya gossypii cells. Eukaryot Cell. 2007 Feb;6(2):182u201397.
Gladfelter AS. Nuclear anarchy: asynchronous mitosis in multinucleated fungal hyphae. Curr Opin Microbiol. 2006 Dec;9(6):547u201352.
Helfer H, Gladfelter AS. AgSwe1p regulates mitosis in response to morphogenesis and nutrients in multinucleated Ashbya gossypii cells. Mol Biol Cell. 2006 Oct;17(10):4494u2013512.
Gladfelter AS. Erratum: Control of filamentous fungal cell shape by septins and formins (Nature Reviews Microbiology (2006) vol. 4 (223-229) 10.1038/nrmicro.1345). Nature Reviews Microbiology. 2006 Apr 1;4(4):318.
Gladfelter AS. Control of filamentous fungal cell shape by septins and formins. Nat Rev Microbiol. 2006 Mar;4(3):223u20139.
Gladfelter AS, Hungerbuehler AK, Philippsen P. Asynchronous nuclear division cycles in multinucleated cells. J Cell Biol. 2006 Jan 30;172(3):347u201362.
Gladfelter AS, Kozubowski L, Zyla TR, Lew DJ. Interplay between septin organization, cell cycle and cell shape in yeast. J Cell Sci. 2005 Apr 15;118(Pt 8):1617u201328.
Gladfelter AS, Zyla TR, Lew DJ. Genetic interactions among regulators of septin organization. Eukaryot Cell. 2004 Aug;3(4):847u201354.
Irazoqui JE, Gladfelter AS, Lew DJ. Cdc42p, GTP hydrolysis, and the cell's sense of direction. Cell Cycle. 2004 Jul;3(7):861u20134.
Irazoqui JE, Gladfelter AS, Lew DJ. Scaffold-mediated symmetry breaking by Cdc42p. Nat Cell Biol. 2003 Dec;5(12):1062u201370.
Gladfelter AS, Bose I, Zyla TR, Bardes ESG, Lew DJ. Septin ring assembly involves cycles of GTP loading and hydrolysis by Cdc42p. J Cell Biol. 2002 Jan 21;156(2):315u201326.
Gladfelter A. A lab with a view: American postdocs abroad. Cell Biol Educ. 2002;1(4):128u201331.
Gladfelter AS, Pringle JR, Lew DJ. The septin cortex at the yeast mother-bud neck. Curr Opin Microbiol. 2001 Dec;4(6):681u20139.
Adamo JE, Moskow JJ, Gladfelter AS, Viterbo D, Lew DJ, Brennwald PJ. Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud. J Cell Biol. 2001 Nov 12;155(4):581u201392.
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