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Christine K. Payne


Associate Professor of Mechanical Engineering and Materials Science

Appointments and Affiliations

  • Associate Professor of Mechanical Engineering and Materials Science
  • Director of Graduate Studies in the Department of Mechanical Engineering and Materials Science
  • Associate Professor of Chemistry

Contact Information

  • Office Location: 701 W. Main St., Office 4306, Chesterfield Building, Durham, NC 27701
  • Office Phone: (919) 681-2096
  • Email Address:
  • Websites:


  • Ph.D. University of California, Berkeley, 2003

Research Interests

Molecular mechanisms by which cells interact with materials, specifically nanoparticles and conducting polymers, with applications in nanomedicine and environmental exposure

Courses Taught

  • CHEM 590: Special Topics in Chemistry
  • ME 392: Undergraduate Projects in Mechanical Engineering
  • ME 394: Engineering Undergraduate Fellows Projects
  • ME 490: Special Topics in Mechanical Engineering
  • ME 555: Advanced Topics in Mechanical Engineering
  • PHYSICS 493: Research Independent Study

In the News

Representative Publications

  • Poulsen, KM; Pho, T; Champion, JA; Payne, CK, Automation and low-cost proteomics for characterization of the protein corona: experimental methods for big data., Analytical and Bioanalytical Chemistry (2020) [10.1007/s00216-020-02726-1] [abs].
  • Jayaram, DT; Payne, CK, Intracellular Generation of Superoxide by TiO2 Nanoparticles Decreases Histone Deacetylase 9 (HDAC9), an Epigenetic Modifier., Bioconjugate Chemistry, vol 31 no. 5 (2020), pp. 1354-1361 [10.1021/acs.bioconjchem.0c00091] [abs].
  • Payne, CK, A protein corona primer for physical chemists., The Journal of Chemical Physics, vol 151 no. 13 (2019) [10.1063/1.5120178] [abs].
  • Morris, JD; Payne, CK, Microscopy and Cell Biology: New Methods and New Questions., Annual Review of Physical Chemistry, vol 70 (2019), pp. 199-218 [10.1146/annurev-physchem-042018-052527] [abs].
  • Jayaram, DT; Kumar, A; Kippner, LE; Ho, PY; Kemp, ML; Fan, Y; Payne, CK, TiO2 nanoparticles generate superoxide and alter gene expression in human lung cells, Rsc Adv., vol 9 no. 43 (2019), pp. 25039-25047 [10.1039/c9ra04037d] [abs].