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Robert W. Carr, Jr., Professor of Biomedical Engineering
Dr. Ramanujam is the Robert W. Carr Professor of Biomedical Engineering, and also a faculty member in the Global Health Institute and Dept. Pharmacology and Cell Biology at Duke University. She is an innovator, educator and entrepreneur and her mission is to develop and leverage technology to have the most wide reaching impact in women’s health. She directs the center for Global Women’s Health Technologies (GWHT), a partnership between the Pratt School of Engineering and the Duke Global Health Institute. Through the GWHT, she is empowering her trainees at Duke and beyond to be agents of change - providing them with the knowledge, confidence and critical thinking skills to create impactful solutions to improve women’s lives.
Dr. Ramanujam’s research focuses on womens’ cancers and in particular breast and cervical cancer. Her goals are to design innovations that enable complex referral services often reserved for hospitals to be accessible at the community/primary care level, develop technologies to see and treat women with early stage disease in one visit and to develop tools that will make cancer treatment more effective and efficient. One example of a technology she and her team has developed to achieve health care impact is the Pocket Colposcope. The Pocket colposcope has the potential to revolutionize cervical cancer screening in low resource communities by enhancing the effectiveness and scalability of the screening process, reducing loss to follow up and guiding treatment decisions.
Design is at the heart of innovation. Today engineering design is often taught in a traditional classroom to engineering students, and often towards the end of a student’s tenure in college. What if design and innovation could be accessible to a global community rather to a privileged few that can attend an elite university and what if the global technological challenges that communities face could be solved by women and girls who can personally relate to them right then and there? Dr. Ramanujam and her team have created a unique model to make design thinking and execution pervasive and in the process have created teachers, innovators and entrepreneurs. It starts with a design course that teaches a small group of students how to hear, create and deliver a technological solution to a community need. Students than adapt the curricula to meet the needs of an international community and teach it to students in those communities using a similar instructor to student ratio. The students in those communities then perpetuate the knowledge by maintaining that virtuous cycle within their own communities.
Women around the world are disproportionately impacted by health, educational and economic inequities. Thus, much of Dr. Ramanujam’s work has a global reach. Countries she and her team have worked in include India, Kenya, Tanzania, Zambia, Peru, Honduras, Guatemala, Haiti and the U.S. These interactions have resulted in a community that is growing exponentially and has an international reach across a number of different sectors including academia, industry, non-governmental organizations and the government.
Prof. Ramanujam has received several awards for her work in cancer research and technology innovation for women's health. She received the TR100 Young Innovator Award from MIT in 2003, the Global Indus Technovator award from MIT in 2005, Era of Hope Scholar awards from the DOD in 2005 and 2009, the Stasnell Family award from the Pratt School of Engineering at Duke in 2011 and the Emerging Leader in Global Health Award from the Consortium of Universities in Global Health (CUGH) in 2018. She is a fellow of several optical and biomedical engineering societies including OSA, SPIE AIMBE. She has also been elected to the National Academy of Inventors - Class of 2018. She is also co-editor of the Handbook of Biomedical Optics (publisher Taylor and Francis).
Appointments and Affiliations
- Robert W. Carr, Jr., Professor of Biomedical Engineering
- Professor of Biomedical Engineering
- Professor of Pharmacology and Cancer Biology
- Affiliate of the Duke Initiative for Science & Society
- Core Faculty in Innovation & Entrepreneurship
- Member of the Duke Cancer Institute
- Office Location: 367 Gross Hall, 140 Science Drive, Durham, NC 27708
- Office Phone: (919) 660-5307
- Email Address: firstname.lastname@example.org
- Ph.D. University of Texas at Austin, 1995
- M.S. University of Texas at Austin, 1992
- B.S. University of Texas at Austin, 1989
Innovating on optical strategies to peer into the biological landscape of thick tissues. Technologies being developed in her lab leverage principles of optical spectroscopy, optical sectioning microscopy, and molecular imaging. Her research group is developing and applying these optically based tools for three problems in cancer: cancer screening in resource-limited settings, intra-operative margin assessment to detect residual disease during cancer surgery, and visualizing tumor hypoxia and metabolism in the context of cancer therapy and drug discovery. Prof. Ramanujam is leading a multi-disciplinary effort to translate these technologies to clinical applications in the breast, and cervix.
Awards, Honors, and Distinctions
- Fellow. International Society for Optics and Photonics. 2013
- Fellow. American Institute for Medical and Biological Engineering. 2012
- Fellow. Optical Society of America. 2010
- BME 230L: Global Women's Health Technologies
- BME 290L: Intermediate Topics with Lab (GE)
- BME 394: Projects in Biomedical Engineering (GE)
- BME 493: Projects in Biomedical Engineering (GE)
- BME 494: Projects in Biomedical Engineering (GE)
- BME 551L: Biomedical Optical Spectroscopy and Tissue Optics (GE, IM)
- BME 899: Special Readings in Biomedical Engineering
- EGR 393: Research Projects in Engineering
- GLHLTH 230L: Global Women's Health Technologies
- GLHLTH 390: Special Topics in Global Health Studies
- GLHLTH 390L-1: Special Topics with Lab in Global Health Studies
- GLHLTH 393: Research Independent Study in Global Health
- GLHLTH 395: Connections in Global Health: Interdisciplinary Team Projects
- GLHLTH 795: Connections in Global Health: Interdisciplinary Team Projects
- MOLCAN 551L: Biomedical Optical Spectroscopy and Tissue Optics (GE, IM)
- PHARM 493: Research Independent Study
- PHARM 494: Research Independent Study
In the News
- The Road to Biomedical Engineering Went Through Brahms (Oct 9, 2018 | Duke Arts)
- Three Engineers Named to National Academy of Inventors (Dec 13, 2017)
- New Tech Promises Easier Cervical Cancer Screening (May 31, 2017 | Pratt School of Engineering)
- Duke Team's Portable Screening Device Takes Aim at Preventable Cervical Cancer Deaths (Feb 15, 2017 | Duke Global Health Institute)
- Researchers Aim to Make Cervical Cancer Screening Accessible to All (Dec 19, 2016)
- Showing Congress the Future of Global Womens Health (Nov 29, 2016)
- New Collaborative Seed Grant Program Gives Eight Awards (Mar 16, 2016)
- Ramanujam Awarded Two Grants to Help Screen for Cervical Cancer in Africa (Aug 25, 2015)
- Duke Announces 2015 Distinguished Professors (May 1, 2015)
- DukeEngage Adds California-Based Programs Targeting Homeless and At-Risk Youth (Oct 2, 2014)
- Ramanujam Named Inaugural Recipient of Carr Professorship (Sep 25, 2014)
- Lab of Entrepreneurial Engineers (Sep 19, 2014)
- Global Research, Domestic Benefits (Jan 13, 2014)
- Duke Launches Global Womens Health Technologies Center (Oct 23, 2013)
- Ramanujam Promoted to SPIE Fellow (Jun 7, 2013)
- Palmer, GM; Zhang, H; Lee, C-T; Mikati, H; Herbert, JA; Krieger, M; von Windheim, J; Koester, D; Stevenson, D; Rocke, DJ; Esclamado, R; Erkanli, A; Ramanujam, N; Dewhirst, MW; Lee, WT, Assessing effects of pressure on tumor and normal tissue physiology using an automated self-calibrated, pressure-sensing probe for diffuse reflectance spectroscopy., Journal of Biomedical Optics, vol 23 no. 5 (2018), pp. 1-8 [10.1117/1.jbo.23.5.057004] [abs].
- Martinez, AF; McCachren, SS; Lee, M; Murphy, HA; Zhu, C; Crouch, BT; Martin, HL; Erkanli, A; Rajaram, N; Ashcraft, KA; Fontanella, AN; Dewhirst, MW; Ramanujam, N, Metaboloptics: Visualization of the tumor functional landscape via metabolic and vascular imaging., Scientific Reports, vol 8 no. 1 (2018) [10.1038/s41598-018-22480-w] [abs].
- Duer, J; Wang, R; Crouch, B; Gallagher, J; Hall, A; Soo, MS; Hughes, P; Haystead, T; Ramanujam, N, Optimizing fluorescently-tethered Hsp90 inhibitor dose for maximal specific uptake by breast tumors, Molecular Guided Surgery: Molecules, Devices, and Applications Iv (2018) [10.1117/12.2285210] [abs].
- Asiedu, MN; Simhal, A; Lam, CT; Mueller, J; Chaudhary, U; Schmitt, JW; Sapiro, G; Ramanujam, N, Image processing and machine learning techniques to automate diagnosis of Lugol's iodine cervigrams for a low-cost point-of-care digital colposcope, Progress in Biomedical Optics and Imaging Proceedings of Spie, vol 10485 (2018) [10.1117/12.2282792] [abs].
- Zhu, C; Martin, HL; Li, M; Crouch, B; Martinez, AF; Palmer, GM; Dewhirst, MW; Ramanujam, N, Non-invasive, simultaneous quantification of vascular oxygenation, glucose uptake and mitochondria membrane potential in a flank tumor model, Optics Infobase Conference Papers, vol Part F91-TRANSLATIONAL 2018 (2018) [10.1364/TRANSLATIONAL.2018.CF2B.2] [abs].