You are here

Michael D Lynch


Assistant Professor in the Department of Biomedical Engineering

Appointments and Affiliations

  • Assistant Professor in the Department of Biomedical Engineering
  • Assistant Professor of Chemistry
  • Faculty Fellow in The Energy Initiative
  • Associate of the Duke Initiative for Science & Society

Contact Information


  • M.D. University of Colorado School of Medicine, 2007
  • Ph.D. University of Colorado - Boulder, 2005

Research Interests

Focused on genetically engineering microbes to shut off their growth circuits and turn on new pathways to produce different compounds—improving production of biofuels, pharmacological molecules and industrial chemicals.

Courses Taught

  • BME 490L: Special Topics in Biomedical Engineering Design (DR)
  • BME 493: Projects in Biomedical Engineering (GE)
  • BME 494: Projects in Biomedical Engineering (GE)
  • BME 590D: Special Topics with Discussion
  • BME 590L: Special Topics with Lab
  • BME 703S: Engineering Management Seminar for Master of Science Students
  • BME 790L: Advanced Topics with the Lab for Graduate Students in Biomedical Engineering
  • BME 791: Graduate Independent Study
  • BME 792: Continuation of Graduate Independent Study
  • ISS 293: ISS Research Independent Study

In the News

Representative Publications

  • Menacho-Melgar, R; Hennigan, JN; Lynch, MD, Optimization of phosphate-limited autoinduction broth for two-stage heterologous protein expression in Escherichia coli., Biotechniques (2021) [10.2144/btn-2021-0055] [abs].
  • Moreb, EA; Lynch, MD, Genome dependent Cas9/gRNA search time underlies sequence dependent gRNA activity., Nature Communications, vol 12 no. 1 (2021) [10.1038/s41467-021-25339-3] [abs].
  • Rios, J; Lebeau, J; Yang, T; Li, S; Lynch, MD, A critical review on the progress and challenges to a more sustainable, cost competitive synthesis of adipic acid, Green Chem., vol 23 no. 9 (2021), pp. 3172-3190 [10.1039/d1gc00638j] [abs].
  • Lynch, MD, The bioprocess TEA calculator: An online technoeconomic analysis tool to evaluate the commercial competitiveness of potential bioprocesses., Metabolic Engineering, vol 65 (2021), pp. 42-51 [10.1016/j.ymben.2021.03.004] [abs].
  • Efromson, JP; Li, S; Lynch, MD, BioSamplr: An open source, low cost automated sampling system for bioreactors, Hardwarex, vol 9 (2021) [10.1016/j.ohx.2021.e00177] [abs].