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Discovering and targeting repeat expansions in human disease

Jan 26

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Thursday, January 26, 2023 - 12:30pm to 1:30pm

Graham Erwin

Presenter

Graham Erwin, PhD

Expansion of a single repetitive DNA sequence, termed a tandem repeat (TR), is known to cause more than 50 diseases. However, repeat expansions are often not explored beyond neurological and neurodegenerative disorders. Here, I will discuss efforts to identify and target repeat expansions in human disease, with a focus on neurodegenerative disease and cancer. Contact Greg Crawford (greg.crawford at duke dot edu) and Debby Silver (debra.silver at duke dot edu) with any questions.