Gabriel Lopez, professor, Dept. of Biomedical Engineering

Monday, April 19, 2010

Gabriel Lopez is a professor in biomedical engineering, with a secondary appointment in mechanical engineering and materials science. He holds a PhD in chemical engineering from the University of Washington and BS in chemical engineering from the University of Colorado. His primary professional interests lie in research and education in biomaterials science and engineering, bioanalytical chemistry and biointerfacial phenomena. These areas are generally populated by researchers with formal training in biomedical engineering, chemical engineering, chemistry, biology and physics, and as such are inherently interdisciplinary and highly collaborative in nature. In the area of research several key accomplishments have had significant impact in their respective fields.

In the area of biomimetic materials, Gabriel's group has developed several intelligent materials systems that are capable of biospecific molecular recognition and transduction of molecular signals to macroscopically observable responses. These materials are finding application in areas such as diagnostics, environmental monitoring and drug discovery.

In the area of biosensing and diagnostic systems, Gabriel has focused on development of methods and instrumentation suited for making measurements on arrays of biospecific and cross-reactive sensors. A key research accomplishment is the development of a suite of methods that span refractometric, fluorometric, electrochemical and colorimetric transduction methods. This comprehensive suite of methodologies brings substantial power to designing biosensing systems for particular applications, and to benchmarking the performance of new methodologies.

In the area of control of microbial interactions with materials, Gabriel's team was among the first to establish principles for formation of fouling resistant surfaces and stimuli-responsive surfaces that could be used for rapid and efficient release of microbial biofilms.

Finally, in the area of analytical separations, he has demonstrated facile methods for the manufacture of integrated nanofluidic systems that allow controllable sample introduction and highly efficient separation using new methodologies such as nanoelectroosmosis. Each of these general areas of research remains ripe for new discoveries and innovations.