BME Seminar - Raj Kothapalli

Mar 26

Thursday, March 26, 2015

11:45 am - 1:00 pm
Teer 115

Translating Photoacoustic Imaging from Bench to Bedside: Optical imaging suffers from poor spatial resolution at depths beyond the optical diffusion limit inside biological tissue. Ultrasound mediated optical imaging technologies, such as ultrasound-modulated optical tomography (UOT) and Photoaocustic Imaging (PAI), have shown great promise in breaking through the diffusion limit to create images of optical contrast of tissue with the resolution of ultrasound. In particular, PAI gained significant attention as it evolved as a multi-scale imaging technology, enabling in vivo imaging from organelles to organs, and tested in clinical studies for breast angiography and mammography. Nevertheless, the development of PAI systems for internal organs (such as prostate) in the clinic has its challenges. In this talk, I will first briefly introduce my doctoral research in the field of UOT. Then I will present the progress achieved during my postdoctoral fellowship on photoacoustic molecular imaging technologies. In particular, I will highlight work on preclinical molecular imaging technologies for numerous diseases and a novel transrectal ultrasound and photoacoustic (TRUSPA) imaging system using capacitive micromachined ultrasonic transducer (CMUT) array technology for human prostate imaging.


Ashley Rasmussen