Nanoparticle-cell interactions: Importance of protein structure
Wednesday, October 1, 2014
1:30 pm - 2:30 pm
French Family Science Center 2237
Dr. Christine Payne
ECE Guest Lecturer. Abstract: Nanoparticles offer exciting new approaches for biomedicine ranging from drug delivery to cellular imaging. In the course of these applications, nanoparticles are exposed to a complex mixture of extracellular proteins that adsorb onto the surface of the nanoparticle. This "protein corona" dominates the interaction of nanoparticles with cells. We have investigated how proteins found in blood serum affect the cellular binding of protein-nanoparticle complexes.